What is Ferulic acid?
Ferulic acid is a ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. It has a role as an antioxidant, a MALDI matrix material, a plant metabolite, an anti-inflammatory agent, an apoptosis inhibitor and a cardioprotective agent. It is a conjugate acid of a ferulate.
|Product Name: ||Ferulic Acid |
|Synonyms: ||trans-Ferulic Acid; Coniferic acid; (E)-Ferulic acid; 4-Hydroxy-3-methoxycinnamic acid |
|CAS: ||1135-24-6 |
|MF: ||C10H10O4 |
|MW: ||194.18 |
|EINECS: ||214-490-0 |
|Product Categories: ||API; Pharmaceutical intermediate; Active Pharmaceutical Ingredients; Intermediates & Fine Chemicals; Pharmaceuticals; Inhibitors; Herb extract; Nervous system drugs |
|Melting point ||168-172 °C(lit.) |
|Boiling point ||250.62°C (rough estimate) |
|density ||1.316(20.0000℃) |
|refractive index ||1.5168 (estimate) |
|storage temp. ||2-8°C |
|pka ||4.58±0.10(Predicted) |
|form ||powder |
|color ||slightly yellow |
|Water Solubility ||soluble |
|InChIKey ||KSEBMYQBYZTDHS-HWKANZROSA-N |
Ferulic acid is a kind of phenolic acid extracted from the resin of ferula asafetida. Ferula asafetida is a kind of Umbelliferae perennial herb with a strong garlic smell and living in sandy areas.
Ferulic acid Applications in Pharmaceuticals:
Ferulic acid has various effects of inhibiting platelet aggregation, expectorant, and inhibition of Mycobacterium tuberculosis and so on. Clinically ferulic acid is mainly applied to the adjuvant treatment of various kinds of vascular diseases such as atherosclerosis, coronary heart disease, cerebrovascular, renal disease, pulmonary hypertension, diabetic vascular disease, and vasculitis as well as neutropenia and thrombocytopenia. It can be used for treating migraine and vascular headache. As a leukocyte-enhancement drug, this drug also has enhanced hematopoietic function. Therefore, ferulic acid may also be for the treatment of leukopenia and thrombocytopenia.
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