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Pemirolast Potassium
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Description
Pemirolast Potassium Description
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Pemirolast potassium 0.1% ophthalmic solution is an effective treatment for allergic conjunctivitis: a pooled analysis of two prospective, randomized, double-masked, placebo-controlled, phase III studies Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel. |
PEMIROLAST POTASSIUM Powder Basic information
| Product Name: | Pemirolast potassium |
| Synonyms: | PEMIROLAST POTASSIUM; 10-methyl-4-(2h-tetrazol-5-yl)-2,6-diazabicyclo[4.4.0]deca-1,3,7,9-tetraen-5-one potassium;2-a)pyrimidin-4-one,9-methyl-3-(1h-tetrazol-5-yl)-4h-pyrido(potassiumsalt;9-methyl-3-(1h-tetrazol-5-yl)-4h-pyrido(1,2-a)pyrimidin-4-onepotassium salt; bmy26517; pemirolast pottassium; tbx; Pemirolast Potassium consulted Standard |
| CAS: | 100299-08-9 |
| MF: | C10H7KN6O |
| MW: | 266.3 |
| Product Categories: | TWT-8152; Bases & Related Reagents; Heterocycles; Intermediates & Fine Chemicals; Nucleotides; Pharmaceuticals; Anti-Allergic |
| Mol File: | 100299-08-9.mol |
PEMIROLAST POTASSIUM Powder Chemical Structure
Pemirolast Potassium Chemical Properties
| Melting point | 310-311°C (dec.) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | H2O: ≥18mg/mL |
| form | powder |
| color | light yellow to yellow with a green cast |
| Merck | 14,7078 |
| CAS DataBase Reference | 100299-08-9(CAS DataBase Reference) |
PEMIROLAST POTASSIUM Powder Usage And Synthesis
| Chemical Properties | Crystalline Solid |
| Uses | Inhibitor of chemical mediator release from tissue mast cells. Antiallergic |
| Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent | |
| Therapeutic Function | Antiallergic, Antiulcer |
Pemirolast potassium Preparation Products And Raw materials
| Raw materials | Ethyl (ethoxymethylene)cyanoacetate–>Sodium hydroxide–>3-Picoline–>4-Bromo-N,N-dimethylaniline–>Potassium hydroxide–>Sodium azide |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
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