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Roxatidine Acetate

  • Chemical Name: Roxatidine acetate
  • CAS No.: 78628-28-1
  • MF:C19H28N2O4
  • MW: 348.44
  • Specification: USP|EP|BP
  • Purity:95%+ or As customer requested
  • Categories: Intermediates & Fine Chemicals;Pharmaceuticals;
  • Test method: HPLC
Category:

Description

What is Roxatidine Acetate?

Roxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.


Roxatidine acetate is a specific and competitive histamine H2 receptor antagonist drug that is used to treat gastric ulcers, Zollinger–Ellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis.[1][2]

Pharmacodynamic studies showed that 150 mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150 mg was more effective than a dose of 75 mg twice daily in terms of inhibiting nocturnal acid secretion.[1]

It was patented in 1979 and approved for medical use in 1986. Roxatidine acetate is available in countries including China, Japan, Korea, Germany, Italy, the Netherlands, Greece and South Africa.


Roxatidine Acetate Basic information 

Product Name: Roxatidine acetate
Synonyms: ROXATIDINE ACETATE;3-[3-(1-piperidylmethyl)phenoxy]propylcarbamoylmethyl acetate;2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-acetamid;2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)acetamide;aceroxatidine;Roxatidine Impurity 5;Altat:TZU-0460;Gastralgin:Roxit
CAS: 78628-28-1
MF: C19H28N2O4
MW: 348.44
Mol File: 78628-28-1.mol

Roxatidina Chemical Structure

Roxatidine acetate            

Roxane Chemical Properties   

Melting point  59-60°
Boiling point  537.3±45.0 °C(Predicted)
density  1.130±0.06 g/cm3(Predicted)
pka 14.23±0.46(Predicted)
CAS DataBase Reference 78628-28-1(CAS DataBase Reference)

Aceroxatidine Usage And Synthesis

Uses Anti-ulcerative.

MSDS: MSDS available

COA: COA can be available if you send us inquiry.

Email us at: info@maxmedchem.com for more details.

Packaging and Shipping

2023082906101618

2023082906101579

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