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Roxatidine Acetate
- Chemical Name: Roxatidine acetate
- CAS No.: 78628-28-1
- MF:C19H28N2O4
- MW: 348.44
- Specification: USP|EP|BP
- Purity:95%+ or As customer requested
- Categories: Intermediates & Fine Chemicals;Pharmaceuticals;
- Test method: HPLC
Description
What is Roxatidine Acetate?
Roxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.
Roxatidine acetate is a specific and competitive histamine H2 receptor antagonist drug that is used to treat gastric ulcers, Zollinger–Ellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis.[1][2]
Pharmacodynamic studies showed that 150 mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150 mg was more effective than a dose of 75 mg twice daily in terms of inhibiting nocturnal acid secretion.[1]
It was patented in 1979 and approved for medical use in 1986. Roxatidine acetate is available in countries including China, Japan, Korea, Germany, Italy, the Netherlands, Greece and South Africa.
Roxatidine Acetate Basic information
Product Name: | Roxatidine acetate |
Synonyms: | ROXATIDINE ACETATE;3-[3-(1-piperidylmethyl)phenoxy]propylcarbamoylmethyl acetate;2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-acetamid;2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)acetamide;aceroxatidine;Roxatidine Impurity 5;Altat:TZU-0460;Gastralgin:Roxit |
CAS: | 78628-28-1 |
MF: | C19H28N2O4 |
MW: | 348.44 |
Mol File: | 78628-28-1.mol |
Roxatidina Chemical Structure
Melting point | 59-60° |
Boiling point | 537.3±45.0 °C(Predicted) |
density | 1.130±0.06 g/cm3(Predicted) |
pka | 14.23±0.46(Predicted) |
CAS DataBase Reference | 78628-28-1(CAS DataBase Reference) |
Aceroxatidine Usage And Synthesis
Uses | Anti-ulcerative. |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
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