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2,6-Pyridinedicarboxylic Acid

  • Chemical Name:2,6-Pyridinedicarboxylic acid
  • CAS No.:499-83-2
  • MF:C7H5NO4
  • MW:167.12
  • Specification: USP|EP|BP
  • Purity: 99% or As customer requested
  • Appearance: white
  • Solubility:5 g/L (20 ºC)
  • Product Categories:Carboxylic Acids;Carboxes;Pyridines;Pyridine;pyridine derivative;Organic acids
  • Test method: HPLC


Dipicolinic acid is a pyridinedicarboxylic acid carrying two carboxy groups at positions 2 and 6. It has a role as a bacterial metabolite. It is a conjugate acid of a dipicolinate(1-). (Source: ChEBI)

Dipicolinic acid Basic information   

Product Name: 2,6-Pyridinedicarboxylic acid
Synonyms: Pyridine-2,6-dicarboxylic acid 98%;2,6-Pyridinedicarboxylic acid solution, Eluent concentrate for IC, 0.02M in water;2,6-PyridinedicarboxylicAcid99%;Pyridine-2,6-dicarboxylicacid,98%;IFLAB-BB F0451-0137;LABOTEST-BB LT00848023;RARECHEM AL BO 1335;PYRIDINE-2,6-DICARBOXYLIC ACID
CAS: 499-83-2
MW: 167.12
EINECS: 207-894-3
Product Categories: Carboxylic Acids;Carboxes;Pyridines;Pyridine;pyridine derivative;Organic acids
Mol File: 499-83-2.mol

Dipicolinic acid Chemical Structure

2,6-Pyridinedicarboxylic acid           

2,6-Dipicolinic acid Chemical Properties     

Melting point  248-250 °C (dec.)(lit.)
Boiling point  295.67°C (rough estimate)
density  1.5216 (rough estimate)
vapor pressure  <0.01 hPa (20 °C)
refractive index  1.6280 (estimate)
Fp  188 °C
storage temp.  Store below +30°C.
solubility  H2O: 1%, clear
pka 2.16(at 25℃)
form  Crystalline Powder
color  White
PH 2.0 (5g/l, H2O, 20℃)
Water Solubility  5 g/L (20 ºC)
BRN  131629
CAS DataBase Reference 499-83-2(CAS DataBase Reference)
NIST Chemistry Reference 2,6-Pyridinedicarboxylic acid(499-83-2)
EPA Substance Registry System 2,6-Pyridinedicarboxylic acid (499-83-2)
2,6-Dipicolinic acid Usage And Synthesis    

Chemical Properties White crystalline powder
Uses Used to prepare dipicolinato ligated lanthanide1 and transition metal2 complexes.
Uses 2,6-Pyridinedicarboxylic acid is an amphoteric polar metabolite produced by many bacterial and fungal species. Prior to its discovery as a microbial metabolite, dipicolinic acid had long been recognised as a chelating agent for many metal ions. Wide distribution of dipicolinic acid among microbes makes it an important dereplication standard in discovery. Dipicolinic acid reaches high concentrations (~10% w/w) in Bacillus endospores aiding heat resistance and is used in laboratories as a marker for the effectiveness of sterilisation.

2,6-Pyridinedicarboxylic acid Preparation Products And Raw materials

Ethyl acetate–>Sulfuric acid–>Potassium permanganate–>2,6-Lutidine–>Heptanedioic acid, 2,6-dioxo—>6-Methyl-2-pyridinecarboxaldehyde–>6-(4-FLUOROPHENYL)PYRIDINE-2-CARBALDEHYDE–>dichromic acid–>DIMETHYL PIMELATE–>trans-Cinnamic acid

MSDS: MSDS available

COA: COA can be available if you send us inquiry.

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