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Cefuroxime Sodium (56238-63-2) C16H15N4O8S.Na

  • Chemical Name: Cefuroxime Sodium
  • CAS No.:56238-63-2
  • MF: C16H15N4O8S.Na
  • MW: 446.37
  • Specification: USP|EP|BP
  • Purity:>98% or As customer requested
  • Color: off-white to white amorphous powder
  • Chemical Properties: White Crystalline Solid
  • Solubility:Freely soluble in water, very slightly soluble in ethanol (96 per cent).
  • Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur&Selenium Compounds; APIs
  • Test method: HPLC

Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis. (Source: NCI Thesaurus (NCIt))

Basic information
Product Name: Cefuroxime sodium
CAS: 56238-63-2
MF: C16H15N4O8S.Na
MW: 446.37
EINECS: 260-073-1
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur&Selenium Compounds; Pharmaceutical intermediate
Chemical Structure

Cefuroxime sodium            

Chemical Properties
Melting point  240-245°C(dec)
alpha  D20 +60° (c = 0.91 in water)
storage temp.  Inert atmosphere,2-8°C
solubility  Freely soluble in water, very slightly soluble in ethanol (96 per cent).
pka pKa (water): 2.5; (DMF): 5.1(at 25℃)
form  neat
Water Solubility  Freely soluble in water
Usage And Synthesis 

Cefuroxime sodium is an off-white to white amorphous powder. Cefuroxime sodium is an injectable second generation, semisynthetic, broad spectrum cephalosporin antibiotic with excellent activity in vitro, enhanced stability to many enterobacterial β-lactamases and favorable pharmacokinetic properties.

Chemical Properties White Crystalline Solid
Uses Cephalosporin antibacterial.
Therapeutic Function Antibiotic

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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