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Cysteamine HCL

  • CAS No.: 156-57-0
    Formula: C12h18clnos
    EINECS: 238-031-9
    Type: Pharmaceutical Intermediates
    Appearance: Powder


What is Cysteamine HCL? 

Cysteamine hcl or cysteamine is a mercaptoethylamine hydrochloride salt reductant that structures in warm blooded creatures from pantetheine development by debasing Coenzyme A. It has been utilized as a cystine draining specialist as well as a somatostatin inhibitor.

Bulk cysteamine hcl has been displayed in vivo to eliminate collected cystine in lysosomes by framing disulfide spans with cystine. The communication among cysteamine and cystine structures cysteine and cysteine-cysteamine blended disulfide which can uninhibitedly leave lysosomes.

Cysteamine hcl has additionally been displayed to hinder somatostatin in any case, the component of activity has not been explained. It is accepted to either repress somatostatin antecedent development or by advancing somatostatin debasement.

Basic information 

Product Name: L-Cystine
Synonyms: cystine; L-Cystin; Cystine acid; L-Dicysteine; Dicysteine; Gelucystine; L-Cystine 99%
CAS: 56-89-3
MF: C6H12N2O4S2
MW: 240.3
EINECS: 200-296-3
Product Categories: Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids; APIs; Biochemical Engineering
Chemical Structure


Chemical Properties


Melting point  >240 °C (dec.) (lit.)
alpha  -224 º(c=2 in 1M HCl)
Boiling point  468.2±45.0 °C(Predicted)
density  1.68
refractive index  -222.5 ° (C=1, 1mol/L HCl)
storage temp.  2-8°C
solubility  1 M HCl: 100 mg/mL
form  Powder/Solid
pka 1.0, 2.1, 8.02, 8.71(at 25℃)
color  White
optical activity [α]20/D 219±5°, c = 1% in 1 M HCl
Water Solubility  0.112 g/L (25 ºC)
Merck  14,2782
BRN  1728094
Stability: Stable. Incompatible with strong oxidizing agents.
Cysteamine HCL Usage And Synthesis

1. Powerful for reducing dull spots

Studies have reliably shown the advantages of cysteamine hcl in noticeably working on the presence of melasma. A 40-patient preliminary uncovered that members involving cysteamine hydrochloride cream experienced huge improvement in their melasma side effects contrasted with those utilizing a fake treatment (Grimes).

Another review included 50 patients utilizing a 5% bulk cysteamine hcl more than four months. Members utilized the cream consistently before bed, and their Melasma Region Seriousness List (MASI) scores were estimated to follow progress. Toward the finish of the 16-week time frame, those utilizing cysteamine cream had fundamentally further developed MASI scores when contrasted with the people who were given a fake treatment (Mansouri).

2. Available without a prescription (OTC)

In September 2020, the Considerations act re-arranged a few meds including hydroquinone, which is viewed as the “highest quality level” depigmenting specialist for treating melasma. Beforehand, hydroquinone was accessible OTC in low fixations. Nonetheless, because of wellbeing concerns connected with inappropriate use as an all-over skin lightener, it is currently just accessible by solution.

The people who made progress in treating their melasma with OTC hydroquinone items might be disappointed at looking for a remedy. Luckily, bulk cysteamine hcl is a powerful yet delicate option for those searching for a nonprescription answer for their melasma.

3. Alright for long haul use

One of the greatest advantages of cysteamine hcl is its reasonableness for long haul use. Numerous other melasma therapies make skin more delicate to daylight; in any case, bulk cysteamine hcl is a protected therapy paying little mind to daylight force. (It is vital to take note of that despite the fact that cysteamine doesn’t increment skin aversion to daylight, going to lengths to safeguard skin from the sun can assist with forestalling further advancement of melasma side effects.)

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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