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Erythromycin Stearate
- Chemical Name:Erythromycin stearate
- CAS No.:643-22-1
- MF: C55H103NO15
- MW:1018.4
- Specification: USP|EP|BPPurity: 98%-99% or As customer requested
- Appearance: white to off-white
- Solubility：ethanol: soluble50mg/mL, clear to very slightly hazy, colorless
- Product Categories:API;Organics;Antibiotics;Macrolides;Pharmaceutical ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;
- Test method: HPLC
Description
Erythromycin Stearate is the stearate salt form of erythromycin, a broad-spectrum, topical macrolide antibiotic with antibacterial activity. Erythromycin stearate diffuses through the bacterial cell membrane and reversibly binds to the 50S subunit of the bacterial ribosome. This prevents bacterial protein synthesis. Erythromycin stearate may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved. (Source: NCI Thesaurus (NCIt))
Erythromycin stearate Basic information
| Product Name: | Erythromycin stearate |
| Synonyms: | qidmycin; sk-erythromycin; ERYTHROMYCIN STEARATE USP(CRM STANDARD); ErythromycinStearate-Bp/Ep/Usp; Erythromycin Stearate; Erythromycin StearateBp/Usp; Eryprim |
| CAS: | 643-22-1 |
| MF: | C55H103NO15 |
| MW: | 1018.4 |
| EINECS: | 211-396-1 |
| Product Categories: | Pharmaceutical ingredients;Intermediates & Fine Chemicals;Pharmaceuticals; Antibiotics;Macrolides;Mechanism of Action; |
| Mol File: | 643-22-1.mol |
Gallimycin Chemical Structure
Eryprim Chemical Properties
| Melting point | 77-79°C |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble50mg/mL, clear to very slightly hazy, colorless |
| form | neat |
| color | white to off-white |
| Stability: | Stable. Combustible. Incompatible with acids, strong oxidizing agents. |
| EPA Substance Registry System | Erythromycin stearate (643-22-1) |
ERYTHROMYCIN STEARATE USP Usage And Synthesis
| Chemical Properties | White Solid |
| Uses | Semi-synthetic macrolide antibiotic. Antibacterial |
| oil lubricant, plasticizer, solvent | |
| Macrodiles antibacterial | |
| Therapeutic Function | Antibacterial |
| General Description | Erythromycin stearate (Ethril, Wyamycin S, Erypar) is thestearic acid salt of erythromycin. Like erythromycin base,the stearate is acid labile. It is film coated to protect it fromacid degradation in the stomach. In the alkaline pH of theduodenum, the free base is liberated from the stearateand absorbed. Erythromycin stearate is a crystalline powderthat is practically insoluble in water but soluble in alcoholand ether. |
| Fluffy colorless powder or fine white powder. | |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | A base. Readily forms salts with acids. |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
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