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L-Tryptophan
- Chemical Name:L-Tryptophan
- CAS No.:73-22-3
- MF:C11H12N2O2
- MW:204.23
- Purity:>98% or As customer requested
- Color:White to yellow-white
- Product Categories: Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids; APIs; Biochemical Engineering
- Test method: HPLC
Description
What is L-tryptophan?
Tryptophan is the least plentiful of all 22 amino acids and an essential amino acid in humans (provided by food), Tryptophan is found in most proteins and a precursor of serotonin. Tryptophan is converted to 5-hydroxy-tryptophan (5-HTP), converted in turn to serotonin, a neurotransmitter essential in regulating appetite, sleep, mood, and pain. Tryptophan is a natural sedative and present in dairy products, meats, brown rice, fish, and soybeans.
L-tryptophan is the L-enantiomer of tryptophan. It has a role as an antidepressant, a nutraceutical, a micronutrient, a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an erythrose 4-phosphate/phosphoenolpyruvate family amino acid, a proteinogenic amino acid, a tryptophan and a L-alpha-amino acid. It is a conjugate base of a L-tryptophanium. It is a conjugate acid of a L-tryptophanate. It is an enantiomer of a D-tryptophan. It is a tautomer of a L-tryptophan zwitterion. (Source: ChEBI)
Basic information
| Product Name: | L-Tryptophan |
| Synonyms: | Tryptophan; L-Tryptophane; Tryptophane; Tryptacin; L-Tryptophan(pharm grade); Pacitron; L-Tryptofan |
| CAS: | 73-22-3 |
| MF: | C11H12N2O2 |
| MW: | 204.23 |
| EINECS: | 200-795-6 |
| Product Categories: | Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids; APIs; Biochemical Engineering |
Chemical Structure
Chemical Properties
| Melting point | 289-290 °C (dec.)(lit.) |
| alpha | -31.1 º (c=1, H20) |
| Boiling point | 342.72°C (rough estimate) |
| density | 1.34 |
| refractive index | -32 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | 20% NH3: 0.1 g/mL at 20 °C, clear, colorless |
| pka | 2.46(at 25℃) |
| form | powder |
| color | White to yellow-white |
| PH | 5.5-7.0 (10g/l, H2O, 20℃) |
| optical activity | [α]20/D 31.5±1°, c = 1% in H2O |
| Water Solubility | 11.4 g/L (25 ºC) |
| Merck | 14,9797 |
| BRN | 86197 |
| Stability: | Stable. Incompatible with strong acids, strong oxidizing agents. |
| InChIKey | QIVBCDIJIAJPQS-VIFPVBQESA-N |
Usage And Synthesis
L-Tryptophan Uses
Amino acids-type drug:
It can be used in amino acid infusion, being often combined with iron and vitamins. Its co-administration with VB6 can improve depression and prevention/treatment of skin disease; as a sleep sedative, it can be combined with L-dopa for the treatment of Parkinson’s disease. It is carcinogenic to experimental animals; it may cause adverse reactions including nausea, anorexia and asthmas. Avoid combination with monoamine oxidase inhibitors.
Nutritional supplements:
Tryptophan contained in egg white protein, fish meat, corn meal and other amino acids are limited; content in cereals such as rice is also low. It can be combined with lysine, methionine and threonine for enhanced amino acids.
Technical Support & Resources
Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
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