Serine

Description

What is Serine?

Serine is a non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)

L-serine is the L-enantiomer of serine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a serine family amino acid, a proteinogenic amino acid, a L-alpha-amino acid and a serine. It is a conjugate base of a L-serinium. It is a conjugate acid of a L-serinate. It is an enantiomer of a D-serine. It is a tautomer of a L-serine zwitterion.

Basic information

Product Name:	L-Serine
Synonyms:	(s)-2-amino-3-hydroxypropanoicacid;2-Amion-3-hydroxypropionicacid;alpha-Amino-beta-hydroxypropionic acid; alpha-amino-beta-hydroxypropionicacid; 8-HYDROXY-L-ALANINE; (S)-Serine; Serinum; Serina; Polyserine
CAS:	56-45-1
MF:	C3H7NO3
MW:	105.09
EINECS:	200-274-3
Product Categories:	Amino Acids;alpha-Amino Acids;Biochemistry;Nutritional Supplements;L-Amino Acids

Chemical Structure

L-Serine

Chemical Properties

Melting point	222 °C (dec.) (lit.)
alpha	15.2 º (c=10, 2N HCl)
Boiling point	197.09°C (rough estimate)
density	1.6
refractive index	1.4368 (estimate)
Fp	150°C
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL
form	powder
pka	2.19(at 25℃)
color	White
PH	5-6 (100g/l, H2O, 20℃)
optical activity	[α]20/D +13.5±0.5°, c = 5% in 5 M HCl
Water Solubility	250 g/L (20 ºC)
λmax	λ: 260 nm Amax: 0.05 λ: 280 nm Amax: 0.05
Sublimation	150 ºC
Merck	14,8460
BRN	1721404
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	MTCFGRXMJLQNBG-REOHCLBHSA-N

Usage And Synthesis

Chemical Properties	Six-sided flaky crystal or prismatic crystal, soluble in water(20℃，25g/100ml water)
Usage	Used as a biochemical reagent and food additive, Used for biochemical research, the preparation of tissue culture, and used as amino acids nutrition medicine.