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  • Chemical Name: 2,4-Thiazolidinedione
  • CAS No.:2295-31-0
  • MF: C3H3NO2S
  • MW:117.13
  • Purity:≥98% or according to customer requested
  • Color:Slightly yellow
  • Product Categories:Pharmaceutical raw materials;pharma; intermediates
  • Test method: HPLC


Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.  1,3-thiazolidine-2,4-dione is a thiazolidenedione carrying oxo substituents at positions 2 and 4. It derives from a hydride of a 1,3-thiazolidine.

Basic information


Product Name: 2,4-Thiazolidinedione
Synonyms: 2,4-Thiazolidinedione, 99% 100GR;2,4-Thiazolidinedione, 99% 25GR;thiazolidin-2,4-dione;2,4-Thiazolidinedione technical grade, 90%; 2,4-thiazolidine dione;
CAS: 2295-31-0
MW: 117.13
EINECS: 218-941-2
Product Categories: Pharmaceutical raw materials; intermediates; pharmaceutical
Chemical Structure


Chemical Properties


Melting point 125-127 °C (lit.)
Boiling point 178-179 °C (19 mmHg)
density 1.408 (estimate)
refractive index 1.5130 (estimate)
Fp 178-179°C/19mm
storage temp. Sealed in dry,Room Temperature
pka 6.50±0.10(Predicted)
form Crystalline Powder
color Slightly yellow
Water Solubility Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.
BRN 110700
Product advantages

– High Purity: Products undergo strict quality control and purification processes to ensure high purity and excellent chemical properties.
– Stability: 2,4-Thiazolidinedione has good stability and is suitable for a variety of experimental conditions and synthesis reactions.
– Customizability: Products of different specifications and packaging can be provided according to customer needs to meet different research and production needs.

The main purpose
  1. Drug Preparation: 2,4-thiazolidinedione is an important intermediate for many drugs, especially in the treatment of diabetes and other metabolic diseases.
  2. Chemical raw materials: As an important catalyst or intermediate in organic synthesis, it is widely used to synthesize different types of compounds.
  3. Agricultural applications: In the field of plant protection, as an important component of some pesticides and fungicides, it helps to increase crop yields and protect plants from diseases.

– Drug research: 2,4-Thiazolidinedione is used as an intermediate in drug synthesis and is used in the research of diabetes drugs (such as rosiglitazone) and the treatment of other metabolic diseases.
– Chemical synthesis: Used as an important intermediate in organic synthesis and used to prepare other organic compounds.
– Scientific research: In the laboratory, as a catalyst, ligand or reaction substance, used to synthesize new compounds or explore new fields.


– Safety Precautions: Please operate in a well-ventilated environment, avoid contact with skin and eyes, and follow correct laboratory operating procedures.
– Storage conditions: Should be stored in a dry, cool, well-ventilated place, away from fire sources and strong oxidants.

Application suggestions

– Drug Research: Precursors or intermediates that can be used to synthesize and explore new diabetes treatment drugs.
– Chemical synthesis: As an important intermediate in organic synthesis reactions, it is used to synthesize compounds with specific structures and properties.
– Scientific Research: Used as reagents, catalysts or ligands in the laboratory to explore new chemical reactions or synthetic pathways.

Final Notes

2,4-Thiazolidinedione is a multifunctional compound with important application value in various fields. Before use, please read the product manual carefully and follow the correct operating steps and safety measures.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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Packaging and Shipping




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