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4-Hydroxyphenylacetic Acid

  • Chemical Name:4-Hydroxyphenylacetic acid
  • CAS No.:156-38-7
  • MF:C8H8O3
  • MW:152.15
  • Purity:≥99% or according to customer requested
  • Color: White to cream or light tan
  • Product Categories: Intermediates & Fine Chemicals;Bulk Drug Intermediates; Pharmaceutical Intermediates
  • Test method: HPLC

What is 4-hydroxyphenylacetic acid?

4-hydroxyphenylacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. It has a role as a plant metabolite, a fungal metabolite, a human metabolite and a mouse metabolite. It is a monocarboxylic acid and a member of phenols. It derives from an acetic acid. It is a conjugate acid of a 4-hydroxyphenylacetate. (Source: ChEBI)

Basic information 
Product Name: 4-Hydroxyphenylacetic acid
Synonyms: (p-hydroxyphenyl)-aceticaci; 4-carboxymethylphenol; 4-Hydroxybenzeneacetic acid; p-hydroxyphenylacetic acid; 4-hydroxyphenylacetate; Parahydroxy phenylacetic acid
CAS: 156-38-7
MF: C8H8O3
MW: 152.15
EINECS: 205-851-3
Product Categories: Carboxylic Acids; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals; Bulk Drug Intermediates; Pharmaceutical Intermediates
Chemical Structure
4-Hydroxyphenylacetic acid            
Chemical Properties    
Melting point  148-151 °C(lit.)
Boiling point  234.6°C (rough estimate)
density  1.2143 (rough estimate)
refractive index  1.4945 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  50g/l
pka 4.50±0.10(Predicted)
form  Crystalline Powder
color  White to cream or light tan
PH 2.0-2.4 (30g/l, H2O, 20℃)
Water Solubility  Soluble in dimethyl sulfoxide and methanol. Slightly soluble in water.
BRN  1448766
4-Hydroxyphenylacetic acid Uses And Synthesis

Organic synthesis intermediate, used to produce β-receptor blocker atenolol and the synthesis of 4,7-dihydroxyisoflavone, the active ingredient of Pueraria lobata daidzein; it can also be used as a pesticide intermediate.

Maxmedchem, a global supplier of 4-Hydroxyphenylacetic acid, 156-38-7 offers for your requirements of RND / Development quantities or commercials, based on status of the product. We can also offer other hot intermediates with supportive technical package required for evaluation.

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