Email Phone Custom Custom


Please enable JavaScript in your browser to complete this form.

4-Hydroxyphenylacetic Acid

  • Chemical Name:4-Hydroxyphenylacetic acid
  • CAS No.:156-38-7
  • MF:C8H8O3
  • MW:152.15
  • Purity:≥99% or according to customer requested
  • Color: White to cream or light tan
  • Product Categories: Intermediates & Fine Chemicals;Bulk Drug Intermediates; Pharmaceutical Intermediates
  • Test method: HPLC


What is 4-hydroxyphenylacetic acid?

4-hydroxyphenylacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. It has a role as a plant metabolite, a fungal metabolite, a human metabolite and a mouse metabolite. It is a monocarboxylic acid and a member of phenols. It derives from an acetic acid. It is a conjugate acid of a 4-hydroxyphenylacetate. (Source: ChEBI)

Basic information 

Product Name: 4-Hydroxyphenylacetic acid
Synonyms: (p-hydroxyphenyl)-aceticaci; 4-carboxymethylphenol; 4-Hydroxybenzeneacetic acid; p-hydroxyphenylacetic acid; 4-hydroxyphenylacetate; Parahydroxy phenylacetic acid
CAS: 156-38-7
MF: C8H8O3
MW: 152.15
EINECS: 205-851-3
Product Categories: Carboxylic Acids; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals; Bulk Drug Intermediates; Pharmaceutical Intermediates
Chemical Structure

4-Hydroxyphenylacetic acid            

Chemical Properties    

Melting point  148-151 °C(lit.)
Boiling point  234.6°C (rough estimate)
density  1.2143 (rough estimate)
refractive index  1.4945 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  50g/l
pka 4.50±0.10(Predicted)
form  Crystalline Powder
color  White to cream or light tan
PH 2.0-2.4 (30g/l, H2O, 20℃)
Water Solubility  Soluble in dimethyl sulfoxide and methanol. Slightly soluble in water.
BRN  1448766
4-Hydroxyphenylacetic acid Uses And Synthesis


Organic synthesis intermediate, used to produce β-receptor blocker atenolol and the synthesis of 4,7-dihydroxyisoflavone, the active ingredient of Pueraria lobata daidzein; it can also be used as a pesticide intermediate.

Maxmedchem, a global supplier of 4-Hydroxyphenylacetic acid, 156-38-7 offers for your requirements of RND / Development quantities or commercials, based on status of the product. We can also offer other hot intermediates with supportive technical package required for evaluation.

a) Free sample can be supplied.

b) Guide our clients by professional knowledge and teach them how to use our product after sales.

c) Accept SGS,BV any other third-party inspection before loading.

d) High quality best price Guaranteed.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

Email us at: for more details.

Packaging and Shipping




Please enable JavaScript in your browser to complete this form.