Email Phone Custom Custom

INQUIRE

Please enable JavaScript in your browser to complete this form.

Benefits of melatonin produced from Maxmedchem

The effect of melatonin for sleep disorders

In 2013, researchers from the University of Sao Paulo in Brazil and Yale University in the United States conducted a meta-analysis (Meta-Analysis) of all studies on melatonin and sleep quality as of that time, and a total of 1683 recipients were included. Participants’ 19 studies were selected and the results showed that compared with placebo, melatonin can shorten the time to fall asleep by an average of 7.06 minutes, increase the total sleep time by an average of 8.25 minutes, and have a certain effect on the quality of sleep. The effect of melanin on improving sleep is obviously weaker than that of prescription drugs, but its advantage is that the effect is not significantly weakened after long-term use, and the side effects are less than that of prescription drugs. There are even reports that melatonin has positive effects other than improving sleep, so it can be used in Have a place in the treatment of sleep disorders.

Melatonin factory-Maxmedchem

N Acetyl 5 methoxytryptamine manufacturer-Maxmedchem

Melatonine distributor-Maxmedchem

From top to bottom are the research summary of melatonin in the time to fall asleep, total sleep time, and sleep quality.

The role of melatonin for cancer treatment

Another role of melatonin that has been widely reported is as an adjuvant therapy in cancer treatment. In 2012, a meta-analysis completed by Chinese researchers was published in Cancer Chemotherapy and Pharmacology. And pharmacology, the article analyzed 8 studies involving 761 subjects. In all 8 studies, the usage of melatonin was a single oral dose of 20 mg per day. It was found that supplementation of melatonin can significantly increase tumors. Complete and partial remission rate, 1-year survival rate, and can reduce the incidence of side effects such as thrombocytopenia, neurotoxicity, fatigue and other side effects of radiotherapy and chemotherapy. However, it is important to note that 6 of the above 8 clinical studies came from the team of Lissoni P and Rovelli F of the University of Milan, Italy. So far, the team has published more than 100 melatonin-related articles. On the one hand, this Of course, it is the result of their long-term work in this field, but many painful experiences in the past also tell us: If the “amazing” results in a certain area are all made by a team and lack repeated verification by other centers, they must be treated with caution.

Melatonin supplement for sale-Maxmedchem

A 2016 systematic review by researchers at the University of Copenhagen in Denmark summarized 37 studies on the protective effect of melatonin on radiation damage. All studies were case-control animal experiments, and the results found that exogenous supplementation Melanin can reduce the level of oxidative stress and inflammation in various organs of animals after radiation exposure, and at the same time improve the survival rate of animals for 30 days and reduce the incidence of radiation enteritis. Only giving melatonin before radiation exposure has the above protective effect. In addition, some studies have conducted theoretical analysis on the role of melatonin in the treatment of specific cancers such as breast cancer and pancreatic cancer from the perspective of molecular signaling pathways. They basically hold a positive view, that is, based on the physiological role of melatonin, it may be These cancers have certain adjuvant treatment effects and can also reduce the side effects of other tumor treatments. However, these conclusions are still mainly based on animal experiments and clinical studies of a few small samples. The evidence needs to be strengthened.

The effect of melatonin for neuropsychiatric disorders

A review published in Current Clinical Pharmacology in 2014 summarized the current research status of melatonin in the treatment of autism spectrum disorders. Four studies have observed that abnormal melatonin levels in the body are related to the severity of autistic behaviors, 20 studies have reported that supplementation of melatonin can improve sleep in patients with autism, and 6 studies have reported that supplementation at night Derived melatonin can improve autistic behavior during the day.

Melatonin Powder-Maxmedchem

Correlative research on the relationship between autistic behavior and melatonin levels in the body

In the same year, an article published in European Neuropsychopharmacology (European Neuropsychopharmacology) summarized the current research status of melatonin in the treatment of depression and depressive symptoms. Analysts believe that although some experiments have yielded positive results, overall From the above point of view, melatonin has not shown obvious therapeutic or preventive effects on depression and depressive symptoms.

The protective effect of topical melatonin for skin damage caused by ultraviolet rays

Another systematic review in 2014 summarized the protective effect of melatonin on skin damage caused by ultraviolet rays. In 4 clinical studies, it was compared with the absence of melatonin. Compared with plain ointment, topical application of melatonin ointment before UV exposure has a protective effect on UV damage, but it has no effect when used after exposure. And 16 molecular and cellular studies have shown that topical use of melatonin can protect cell structure and signal pathway damage caused by ultraviolet rays.

My conclusion:

1. The effect of melatonin on improving sleep is mild but more certain.

2. Studies have reported the positive effects of melatonin on some diseases such as tumors and autism, but the strength of the evidence is not high. It can be considered that melatonin has further research value in these fields, but it is not suitable for clinical use. in accordance with.

3. Short-term use of melatonin is safe, and the main side effects are mild discomfort such as dizziness, headache, nausea, and drowsiness. The safety of long-term use of melatonin in children and adolescents remains to be studied, and women who are pregnant and breastfeeding should not use melatonin.

For more details about melatonin powder, melatonin supplements, please feel free to contact us at info@maxmedchem.com

LEAVE MESSAGE

Please enable JavaScript in your browser to complete this form.