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Doripenem Hydrate (364622-82-2) C15H26N4O7S2

  • Chemical Name: Doripenem hydrate
  • CAS No.: 364622-82-2
  • MF: C15H26N4O7S2
  • MW: 438.51
  • Specification: USP|EP|BP
  • Purity:98%,99% or As customer requested
  • Appearance: white to beige
  • Solubility:H2O: soluble5mg/mL, clear (warmed)
  • Product Categories: Inhibitors
  • Test method: HPLC

A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.

Doripenem Monohydrate Basic information


Product Name: Doripenem hydrate
Synonyms: (+)-(4r,5s,6s)-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-3-[[(3s,5s)-5-[(sulfamoylamino)-methyl]-3-pyrrolidinyl]thio]-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate; doripenem hydrate; DoripeneM Crude; 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate; (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Doripenem monohydrate, >=99%; (4R,5S,6S)-6-((R)-1-Hydroxyethyl)-4-methyl-7-oxo-3-(((3S,5S)-5-((sulfamoylamino)methyl)pyrroli; S 4661 monohydrate
CAS: 364622-82-2
MF: C15H26N4O7S2
MW: 438.51
EINECS: 680-392-3
Product Categories: Doribax, Doripenem monohydrate, S-4661, Finibax; Inhibitors
Mol File: 364622-82-2.mol

Doripenem Hydrate Chemical Structure

Doripenem hydrate            

Doripenem Monohydrate Chemical Properties     
Melting point  173°C(dec.)(lit.)
storage temp.  2-8°C
solubility  H2O: soluble5mg/mL, clear (warmed)
form  powder
color  white to beige
BRN  15340136
CAS DataBase Reference 364622-82-2(CAS DataBase Reference)

Doripenem Hydrate Usage And Synthesis          

Doripenem (doripenem monohydrate) is an ultra-broad spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It is particularly active against Pseudomonas aeruginosa.

MSDS: MSDS available

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