Doxycycline Hyclate

  • Chemical Name: Doxycycline hyclate
  • CAS No.: 24390-14-5
  • MF: C24H31ClN2O9
  • MW: 526.97
  • Specification: USP|EP|BP
  • Purity:>98% or As customer requested
  • Color: yellow to greenish-yellow
  • Solubility:H2O: soluble50mg/mL
  • Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals; APIs; Quinuclidines;
  • Test method: HPLC


Doxycycline Hyclate is the hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity.

Doxycycline hyclate Basic information

Product Name: Doxycycline hyclate
Synonyms: Doxycycline Hyclate USP; DOXYCYCLINE HYCLATE USP GRADE; Doxycycline Hydrochlocide; Doxycycline HCL;
CAS: 24390-14-5
MF: C24H31ClN2O9
MW: 526.97
EINECS: 2017-001-1
Product Categories: Pharmaceuticals; Pharmaceutical intermediate; Amines; Aromatics; Intermediates & Fine Chemicals; Pharma; Drug bulk; Antibiotic Explorer; Quinuclidines; Pharmaceutical intermediates

Doxycycline hyclate Chemical Structure

Doxycycline hyclate            

Periostat Chemical Properties 

Melting point  About 201 °C
alpha  D25 -110° (c = 1 in 0.01N methanolic HCl)
RTECS  QI8925000
storage temp.  Store at +4°C
solubility  H2O: soluble50mg/mL
form  Yellow to yellow-green crystalline solid
color  yellow to greenish-yellow
Water Solubility  Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chloroform and ether.
Merck  14,3440
BRN  5702728

Periostat Usage And Synthesis

Chemical Properties Yellow Solid


tetracycline antibiotics group
Tetracycline antibacterial.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.         

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