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ZANAMIVIR HYDRATE (139110-80-8) C12H20N4O7

  • Chemical Name:ZANAMIVIR HYDRATE
  • CAS No.:139110-80-8
  • MF: C12H20N4O7
  • MW:332.31
  • Specification: USP|EP|BP
  • Purity:>98% or As customer requested
  • Color: white to beige
  • Solubility:H2O: soluble10mg/mL, clear
  • Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;APIs
  • Test method: HPLC
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ZANAMIVIR HYDRATE is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles. It was launched as Relenza in Australia for treatment of human influenza A and B virus infections.

Human studies have shown that zanamivir is effectivewhen administered before or after exposure to the influenzavirus. If administered before exposure to the virus, the drugreduced viral propagation, infectivity, and disease symptoms.If administered after exposure, the drug reduces propagation,viral titer, and illness. 

Zanamivir Hydrate 98 Basic information   
Product Name: ZANAMIVIR HYDRATE
Synonyms: ZANAMIVIR; 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid; 
CAS: 139110-80-8
MF: C12H20N4O7
MW: 332.31
EINECS: 691-117-1
Product Categories: Inhibitors; Anti-virals; Anti-viral Compounds; Intermediates & Fine Chemicals; Pharmaceuticals

Zanamivir Hydrate 98 Chemical Structure

ZANAMIVIR HYDRATE            

Zanamivir Hydrate Chemical Properties  
Melting point  2560C (dec.)
alpha  D20 +40.9° (c = 0.9 in water)
density  1.75±0.1 g/cm3(Predicted)
storage temp.  -20°C Freezer
solubility  H2O: soluble10mg/mL, clear
form  powder
pka 3.82±0.70(Predicted)
color  white to beige
optical activity [α]/D +30 to +40°, c = 1 in H2O
InChIKey ARAIBEBZBOPLMB-UFGQHTETSA-N

Zanamivir Hydrate Usage And Synthesis


Chemical Properties Colorless Crystalline Solid

Uses

Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral
antineoplastic, anti-metabolite
Therapeutic Function Antiviral
Pharmaceutical Applications A synthetic neuraminidase inhibitor formulated for administration by inhalation.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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