Author:Site Editor Publish Time: 2021-09-29 Origin:Site
Finasteride mainly inhibits type II 5α reductase, thereby reducing the content of dihydrotestosterone. Under the action of 5α reductase, testosterone is transformed into the more active androgen dihydrotestosterone (DHT). Dihydrotestosterone inhibits hair growth, leading to androgen hair loss. Finasteride is a 5α reductase inhibitor. By inhibiting 5α reductase, it reduces the DHT content in serum and scalp by 60%-70%, thereby preventing DHT from damaging the dermal papilla and fundamentally controlling and curing hair loss.
Earlier, researchers conducted a double-blind experiment of finasteride and placebo: 1.7% of 945 male patients treated with finasteride discontinued treatment due to adverse reactions.
Among the adverse reactions involved, the effect of finasteride on hair loss patients is most criticized as the effect on sexual function, but in FDA data, this effect is extremely low, which is about 2%. Among the patients actually exposed, a considerable number of people have symptoms of decreased sexual desire at the beginning of use, but more than 95% of the symptoms will disappear or be significantly reduced after continued use.
Therefore, finasteride is generally well tolerated, and the adverse reactions are usually mild, and it is generally not necessary to discontinue treatment. It can be used for a long time as long as it is a healthy liver function, and it will not cause harm to the body.
(1) Attitude adjustment, you need to know that many times the side effects are psychological. Murphy's theorem tells you that the more you are afraid of side effects, the more likely you encounter side effects;
(2) Zinc supplementation or grape seed extract can be used as aromatase inhibitor to resist the increase of estrogen, thereby reducing side effects;
(3) Actively exercise. If you are overweight, you should actively lose weight. Do aerobic exercise as much as possible. If you take finasteride, you can exercise properly;
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