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Fingolimod

  • Chemical Name: Fingolimod
  • CAS No.:162359-55-9
  • MF: C19H33NO2
  • MW: 307.47
  • Purity: ≥98% or according to customer requested
  • Color: white to beige
  • Product Categories: pharmaceutical intermediate;API
  • Test method: HPLC
Category:

Description

What is Fingolimod?

Fingolimod is an aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate. It has a role as an immunosuppressive agent, a prodrug, an antineoplastic agent, a sphingosine-1-phosphate receptor agonist and a CB1 receptor antagonist. It is an aminodiol and a primary amino compound. It is a conjugate base of a fingolimod(1+). (Source: ChEBI)

Introduction  

Product Name: Gilenia
Synonyms: Gilenia; Fingolimod; FingoliMod Base; fenogliMod;
CAS: 162359-55-9
MF: C19H33NO2
MW: 307.47
EINECS: 1308068-626-2
Product Categories: pharmaceutical intermediate; API
Chemical Structure

Fingolimod            

Chemical Properties   

Melting point 103-105°
Boiling point 479.5±45.0 °C(Predicted)
density 1.016
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Fingolimod Uses And Synthesis

Fingolimod is an orally available immunomodulatory drug used to treat relapsing multiple sclerosis. Fingolimod is associated with transient serum enzyme elevations during therapy and with rare instances of clinically apparent, acute liver injury that can be severe and even fatal.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

Email us at: info@maxmedchem.com for more details.

Packaging and Shipping

2023082906101618

2023082906101579

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