In the field of nutrition, histidine is considered to be an essential amino acid for humans, mainly for children. After many years of development, humans can begin to synthesize it by themselves, and at this time it becomes a non-essential amino acid. Adding a small amount of histidine to the diet of patients with chronic uremia will increase the rate of amino acid binding into hemoglobin and reduce nephrogenic anemia.
Therefore, histidine is also an essential amino acid for patients with uremia. Under the action of histidine decarboxylase, histidine is decarboxylated to form histamine. Histamine has a strong vasodilator effect, and is related to a variety of allergies and inflammation. In addition, histamine stimulates pepsin and gastric acid.
Have you ever heard about L-histidine?
L-histidine is a semi-essential amino acid, which is especially important for the growth of infants and animals. It can be used as a biochemical reagent and medicament, and can also be used to treat heart disease, anemia, rheumatoid arthritis and other drugs. Histidine is found in bananas, grapes, meat, poultry, milk and dairy products. In addition, histidine is also present in green vegetables, but the content is less.
Pharmacological action of Istidina
The imidazole group of histidine can form coordination compounds with Fe2+ or other metal ions to promote the absorption of iron, so it can be used to prevent and treat anemia. Histidine can reduce the acidity of gastric juice, ease the pain of gastrointestinal surgery, relieve vomiting and stomach burning during pregnancy, inhibit digestive ulcers caused by autonomic nervousness, and it is also effective for allergic diseases such as asthma. In addition, histidine can dilate blood vessels and lower blood pressure. It is clinically used for the treatment of angina pectoris and cardiac insufficiency. The histidine content in the blood of patients with rheumatoid arthritis decreased significantly. After using histidine, it was found that their grip strength, walking, and erythrocyte sedimentation rate were all improved.
The level of histidine in the body must be balanced to ensure a good mental state and physical health. Studies have shown that high levels of this amino acid are associated with mental disorders (such as anxiety and schizophrenia), while low levels of histidine are thought to help develop rheumatoid arthritis and deafness caused by nerve damage. For this reason, histidine supplements can help relieve the symptoms of rheumatoid arthritis.
Histidine is very important for maintaining normal sexual function because it is converted into histamine, a chemical required to stimulate sexual desire. Together with vitamin B3 (niacin) and vitamin B6 (pyridoxine), histidine can increase sexual pleasure by increasing the body’s histamine levels. Histamine helps the immune system to sense allergic reactions and promotes the production of gastric juice for normal digestion.
Studies have shown that the role of histidine also includes its use as a natural antidote, which can effectively prevent radiation damage and eliminate heavy metals from the system. It even helps prevent AIDS, because histidine is an essential element for the production of red blood cells and white blood cells.
Like other amino acids, histidine can be found in many high-protein foods, such as meat and dairy products, and grains such as rice, wheat, and rye. It has not yet been determined whether it is a non-essential amino acid, but health experts agree that although the body can make histidine on its own, it is prone to shortages. Patients with chronic diseases, post-operative patients, and arthritis patients can consider supplementing histidine with nutritional supplements.
Since it has been proven to have an effect on the central nervous system, patients with bipolar disorder should not take this histidine supplement without consulting a doctor. In addition, people with liver and kidney diseases should also supplement these nutrients in consultation with a doctor. Like any type of amino acid supplement, excessive intake of histidine can also cause an imbalance of nitrogen in the body and disrupt the normal function of the liver and kidneys to remove toxins.
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