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Ivabradine(155974-00-8)C27H36N2O5

  • Chemical Name: Ivabradine
  • CAS No.:155974-00-8
  • MF:C27H36N2O5
  • MW:468.59
  • Purity:≥98% or according to customer requested
  • Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API;
  • Test method: HPLC
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What is Ivabradine?

Ivabradine is a small molecule inhibitor of the If ion channel which is used to decrease the heart rate in patients with symptomatic heart failure who have a resting heart rate above 70 beats per minute despite optimal doses or intolerance of beta blockers. Ivabradine has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.(Source: LiverTox)

Introduction    
Product Name: Ivabradine
Synonyms: 3-[3-[[(8S)-3,4-dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methyl-amino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;3-[3-[[(8S)-3,4-dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;Ivabradine;Ivabridine –;7-(3-((((R)-4,5-diMethoxy-1,2-dihydrocyclobutabenzen-1-yl)Methyl)(Methyl)aMino)propyl)-2,3-diMethoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-one;Ivabradine sulfate;Ivabradine(Hydrochloride form);2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-; Ivabradine HCl; ivabradin
CAS: 155974-00-8
MF: C27H36N2O5
MW: 468.59
Product Categories: API; Pharmaceuticals
Chemical Structure

Ivabradine           

Chemical Properties
Boiling point  626.9±55.0 °C(Predicted)
density  1.146±0.06 g/cm3(Predicted)
pka 8.77±0.50(Predicted)
         
Ivabradine Uses

Ivabradine is a first selective and specific If inhibitor that was approved by EMEA in November for symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm. This is the first agent to lower heart rate by inhibiting the cardiac pacemaker If current. The compound was discovered and developed by Servier and is currently being marketed in Ireland.    


Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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