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  • Chemical Name:L-Isoleucine
  • CAS No.:73-32-5
  • MF:C6H13NO2
  • MW:131.17
  • Purity:>98% or As customer requested
  • Color:White to Off-white
  • Product Categories:Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids; APIs; Biochemical Engineering
  • Test method: HPLC


What is Isoleucine?

Isoleucine, an amino acid that makes up between 2% and 10% of most proteins, is a common one. Isoleucine amino acid, one of several so-called essential amino acids for humans, rats, and other higher animals, was first isolated from fibrin, a blood clot-forming protein, in 1904.i.e., they need food sources because they can’t make it. Isoleucine amino acid is made in plants and microorganisms from the amino acid threonine.

Basic information   

Product Name: L-Isoleucine
Synonyms: Isoleucine; (S)-Isoleucine; L-(+)-Isoleucine; Isoleucinum; Isoleucina; 
CAS: 73-32-5
MF: C6H13NO2
MW: 131.17
EINECS: 200-798-2
Product Categories: Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids; APIs; Biochemical Engineering
Chemical Structure


Chemical Properties   

Melting point  288 °C (dec.) (lit.)
alpha  41 º (c=4, 6N HCl)
Boiling point  225.8±23.0 °C(Predicted)
density  1.2930 (estimate)
refractive index  40.5 ° (C=4, 6mol/L HCl)
Fp  168-170°C
storage temp.  Store below +30°C.
solubility  1 M HCl: 50 mg/mL
pka 2.32, 9.76(at 25℃)
form  powder
color  White to Off-white
PH 5.5-6.5 (40g/l, H2O, 20℃)
optical activity [α]20/D +41.0±1°, c = 5% in 6 M HCl
Water Solubility  41.2 g/L (50 ºC)
λmax λ: 260 nm Amax: 0.07
λ: 280 nm Amax: 0.05
Sublimation  168-170 ºC
Merck  14,5179
JECFA Number 2118
BRN  1721792
Isoleucine Usage And Synthesis

L-Isoleucine Uses            

The immune system, including cells, immune organs, and reactive substances, can be enhanced by isoleucine.Host defense peptides known as -defensins, which have the ability to regulate both innate and adaptive immunity, have also been shown to be induced by isoleucine, according to recent research.

By increasing the expression of -defensins, isoleucine amino acid administration can also reverse the effects of some pathogens on human and animal health. As a result, the purpose of this review is to summarize the connection between immune functions and branched chain amino acids while also emphasizing the impact of isoleucine on immunity.

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