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Levamisole
- Chemical Name: Levamisole
- CAS No.: 14769-73-4
- MF: C11H12N2S
- MW: 204.29
- Purity: ≥98% or according to customer requested
- Product Categories: Pharmaceutical raw materials;APIs;Antiparasitic drugs
- Test method: HPLC
Description
What is Levamisole?
Levamisole is an antihelminthic drug that was commonly used for the treatment of parasitic, viral, and bacterial infections. It was manufactured by Janssen and first used in 1969 as an agent to treat worm infestations Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer. Prior to this, levamisole was used as an antirheumatic therapy in the 1970s and 1980s for patients with rheumatoid arthritis. Because of its immunomodulatory effects, this drug has been studied in the treatment of various immune-mediated diseases, with some studies showing positive results.
This drug has also been used in combination with other drugs for the treatment of various cancers. Levamisole was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. Interestingly, levamisole has been found as an adulterant in cocaine and can lead to a variety of adverse effects in individuals using this drug.
Basic Information
| Product Name: | Levamisole |
| Synonyms: | Levamisolum; Levamisol; Levamisole Base; |
| CAS: | 14769-73-4 |
| MF: | C11H12N2S |
| MW: | 204.29 |
| EINECS: | 238-836-5 |
| Product Categories: | Pharmaceutical raw materials;APIs;Antiparasitic drugs |
Chemical Structure
Chemical Properties
| Melting point | 60-61.5° |
| alpha | D25 -85.1° (c = 10 in chloroform) |
| Boiling point | 344.4±45.0 °C(Predicted) |
| density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| pka | 10.00±0.40(Predicted) |
Levamisole Uses
Levamisole is an anthelmintic drug. Co-administered with fluorouracil in the treatment of Dukes’ stage C colon cancer, levamisole restores immune function through stimulating antibody formation, enhancing T-cell activity, and potentiating macrophage function.
It is used for initial and secondary immunodeficient conditions, autoimmune diseases, chronic and reoccurring infections, large intestine adenocarcinoma, helmintosis, and rheumatoid arthritis.
Technical Support & Resources
Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
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