Prilocaine

Description

Prilocaine is an amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic. It has a role as a local anaesthetic and an anticonvulsant. It is an amino acid amide and a monocarboxylic acid amide.

The amide local anesthetics including lidocaine, bupivacaine and ropivacaine are commonly used for pain control during minor surgery or invasive procedures such as biopsies, small excisions or dental work. These local anesthetics have not been linked to serum enzyme elevations, but when given as constant infusions or repeated injections have been occasionally mentioned as possible causes of clinically apparent liver injury.

basic information

Product Name:	Prilocaine
Synonyms:	Propitocaine; Prilocainum; prilocaine base
CAS:	721-50-6
MF:	C13H20N2O
MW:	220.31
EINECS:	211-957-0
Product Categories:	Pharmaceutical Intermediates;Inhibitors;Active Pharmaceutical Ingredients;research chemical;API

Chemical Structure

Prilocaine

Chemical Properties

Melting point	37-38°
Boiling point	bp0.1 159-162°
density	1.0117 (rough estimate)
refractive index	nD20 1.5298
storage temp.	2-8°C
solubility	Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent).
form	neat
pka	pKa 7.32 or 7.89 (Uncertain)
Water Solubility	6.169g/L(25 ºC)

Prilocaine Uses

It is a kind of local anesthetic drug. The product has better efficacy than procaine and the local anesthesia intensity and speed being similar as lidocaine but with longer duration time and less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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