Sulbactam Sodium

Description

What is Sulbactam Sodium?

Sulbactam Sodium is the sodium salt form of sulbactam, a beta-lactam with weak antibacterial property. Sodium sulbactam contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics.

Combining this agent with a beta-lactamase sensitive antibiotic such as penicillins and cephalosporins against penicillinase-producing and beta-lactamase-producing organisms, results in a decreased turnover rate of the sensitive antibiotic and enhances its antibacterial property.

Sulbactam Sodium Basic information

Product Name:	Sulbactam sodium
Synonyms:	SULBACTAM SODIUM; SULBACTAM SODIUM SALT; sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide; SODIUM SULBACTAM; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI); Antibiotic medicine CAS 69388-84-7 veterinary sulbactam sodium; (2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3,2,0]heptane-2-carboxylic acid 4,4-dioxide sodium salt; Sulbatam Sodium
CAS:	69388-84-7
MF:	C8H12NNaO5S
MW:	257.24
EINECS:	273-984-4
Product Categories:	pharmaceutical raw material; Antibiotic; Pharma;Chiral Reagents; Pharmaceutical raw materials; Inhibitors; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds; API; APIs
Mol File:	69388-84-7.mol

Combactam Chemical Structure

SULBACTAM SODIUM SALT Chemical Properties

Melting point	>230°C (dec.)
storage temp.	-20°C Freezer, Under Inert Atmosphere
solubility	Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids.
form	neat
InChIKey	NKZMPZCWBSWAOX-IBTYICNHSA-M
CAS DataBase Reference	69388-84-7(CAS DataBase Reference)

SODIUM SULBACTAM Usage And Synthesis

Description	Sulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.
Chemical Properties	White Solid
Uses	Ampicillin and sulbactam sodium infusion comes as a powder to be blended in with fluid and infused intravenously (into a vein) or intramuscularly (into a muscle) like clockwork (multiple times everyday). The length of treatment relies upon the kind of disease you have. Your primary care physician will let you know how long to utilize pharmaceutical raw material sulbactam sodium. After your condition improves, your PCP might change you to one more anti-infection that you can take by mouth to finish your treatment. You might get sodium sulbactam infusion in a clinic, or you might utilize the medicine at home. In the event that you will utilize pharmaceutical raw material sulbactam sodium infusion at home, your medical care supplier will tell you the best way to utilize the prescription. Be certain that you grasp these headings, and inquire as to whether you have any inquiries. You ought to start to feel significantly improved during the initial not many long periods of treatment with ampicillin and sulbactam infusion. On the off chance that your side effects don’t improve or on the other hand assuming they deteriorate, call your PCP. In the event that you actually have side effects of disease after you finish ampicillin and sulbactam infusion, tell your primary care physician. Use sulbactam sodium infusion until you finish the remedy, regardless of whether you feel significantly improved. Assuming you quit utilizing ampicillin and sulbactam infusion too early or on the other hand in the event that you skip dosages, your contamination may not be totally treated and the microbes might become impervious to anti-microbials.
Therapeutic Function	Beta-lactamase inhibitor