At Maxmedchem, we are a wholesale bulk berberine hcl powder supplier offering competitive factory-direct prices and consistent pharmaceutical-grade. Our berberine powder delivers reliable purity, potency, and consistency to nutraceutical brands and ingredient distributors worldwide.
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Looking for a reliable Berberine HCL Bulk Supplier to support your supplement or pharmaceutical business?
What is The Source of Berberine HCL?
Berberine is a natural isoquinoline alkaloid extracted from various medicinal plants, primarily:
- Berberis aristata (Tree turmeric)
- Berberis vulgaris (Barberry)
- Coptis chinensis (Chinese goldthread)
- Hydrastis canadensis (Goldenseal)
These plants have been traditionally used in Ayurvedic and Chinese medicine for their antimicrobial, anti-inflammatory, and metabolic health properties.
Berberine HCL Manufacturing Process
Maxmedchem employs ISO-certified extraction and purification techniques to ensure hig.
1. Raw Material Selection
Carefully sourced Berberis/Coptis plant roots and rhizomes.
2. Solvent Extraction
Ethanol or water-based extraction to pull out alkaloids.
3. Filtration & Concentration
Crude extract filtered and concentrated under vacuum.
4. Purification
Column chromatography used to isolate pure berberine.
5. Conversion to HCL Salt
Berberine base reacted with hydrochloric acid to form Berberine Hydrochloride (HCL).
6. Drying & Milling
Spray-dried and milled into fine yellow crystalline powder (≥98% purity).
Our QC team runs full COA, HPLC, and microbial tests for every lot.
Berberine HCL Powder Specification
| Product Name | Berberine Hydrochloride (HCL) Powder |
| Botanical Source | Berberis aristata / Coptis chinensis |
| CAS Number | 633-65-8 |
| Molecular Formula | C20H18ClNO4 |
| Molecular Weight | 371.82 |
| Appearance | Bright yellow fine crystalline powder |
| Assay (HPLC) | ≥ 98% |
| Odor & Taste | Characteristic, bitter |
| Loss on Drying | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 10 ppm |
| Lead (Pb) | ≤ 2 ppm |
| Arsenic (As) | ≤ 1 ppm |
| Mercury (Hg) | ≤ 0.1 ppm |
| Cadmium (Cd) | ≤ 1 ppm |
| Microbial Limit | < 1000 cfu/g (total plate count) |
| Yeast & Mold | < 100 cfu/g |
| E. coli / Salmonella | Negative |
| Packaging | 25 kg/drum (food-grade fiber drum with PE bag) |
| Shelf Life | 24 months when properly stored |
| Storage | Store in a cool, dry place, away from light and moisture |
Berberine HCL Supplement Formulation Ideas
1. Delivery Formats
- 500 mg vegetarian capsules
- 1000 mg tablets (with piperine for enhanced bioavailability)
- Functional drink powders or sachets
- Herbal complex blends (with curcumin, milk thistle, or cinnamon extract)
2. Typical Dosage
- 500 mg – 1500 mg daily, divided into 2–3 doses
3. Formulation Tips
- Include bioavailability enhancers (piperine)
- Use enteric coating for better gastrointestinal tolerance
- Combine with stabilizing excipients to maintain potency
What Maxmedchem Provides to Distributors & Importers
When you wholesale bulk berberine hcl powder suppliers In Maxmedchem, you gain:
High Purity (≥98%) COA & third-party test reports
Support FDA, ISO, Halal, Kosher, Halal certified manufacturing
Global export service with full documentation (MSDS, TDS, COA)
Bulk supply from 25kg drum MOQ for large-scale orders
We are committed to long-term B2B partnerships with ingredient traders, contract manufacturers, and brand owners worldwide. Contact us today for a competitive quote and sample!
Also See
- Why Berberine Is a Must-Have Ingredient for Blood Sugar and Gut Health Formulas
- Why Berberine Extract is the Must-Have Ingredient in Cosmetic Formulations
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- Pharmaceutical Companies How to Find Berberine Suppliers
- What is The Difference Between Berberine and Berberine HCL
- Is Berberine Better at Night or Morning:Ingredients Guide
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