Wholesale Vitamin B12 (Cyanocobalamin) 99% Powder USP In USA Price

Pure Vitamin B12 Powder particularly in the form of Cyanocobalamin, plays a vital role in energy metabolism, red blood cell formation, and neurological function. As consumer demand for health and wellness products continues to rise, the market for Vitamin B12 Cyanocobalamin 99% Powder USP has expanded rapidly in the USA. Explore wholesale vitamin b12 cyanocobalamin 99% powder usp pricing in the USA. Discover its source, manufacturing process, commercial uses, and supplement industry case studies for B2B buyers.

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What is USP Grade?

USP grade refers to a quality standard set by the United States Pharmacopeia (USP)—a scientific nonprofit that sets benchmarks for the identity, strength, purity, and quality of medicines, dietary supplements, and food ingredients.

✅ What “USP Grade” Means:

Meets USP specifications: The ingredient complies with rigorous quality and purity standards listed in the official USP–NF monograph.

Tested for contaminants: Includes limits on heavy metals, microbial content, residual solvents, and other impurities.

Identity verification: Proven to be the correct compound via validated testing methods.

Used in pharma and supplements: Acceptable for use in products that go into the human body, including:

Pharmaceuticals
Nutritional supplements
Fortified foods

✅ USP Grade vs Food Grade vs Technical Grade

Criteria	USP Grade	Food Grade	Technical Grade
Definition	Meets United States Pharmacopeia standards	Meets FDA standards for safe food use	Industrial-grade, not intended for consumption
Purity	Very high (typically ≥99%)	High (usually ≥95–98%)	Variable (can be <95%)
Use Case	Pharmaceuticals, supplements, injections	Food and beverage additives, nutraceuticals	Industrial use: cleaners, cosmetics, lab use
Safety Testing	Rigorously tested for heavy metals, microbes, solvents	Tested for safety in food applications	May not be tested for ingestion or consumption
Regulatory Approval	FDA, USP, and sometimes EP compliant	FDA or EFSA approved for food use	Not approved for ingestion
Documentation	COA, MSDS, USP Monograph, GMP, ISO certs	COA, MSDS, food safety compliance docs	Often limited documentation
Price	Highest	Moderate	Lowest
Manufacturing Standards	GMP, pharmaceutical-grade facilities	Food-grade production lines	Basic industrial production
Shelf Life & Stability	Strictly controlled	Controlled	May vary widely
Examples of Use	B12 injections, capsules, IV therapy	Fortified cereals, beverages, gummies	Paints, coatings, industrial processes

Where Source of Vitamin B12 Cyanocobalamin?

Cyanocobalamin is a synthetic, stable form of Vitamin B12 produced by microbial fermentation. Although naturally occurring B12 is found in animal products like liver, fish, eggs, and dairy, industrial production relies on bacterial fermentation, making it suitable for vegetarian and vegan supplements.

The primary organisms used in fermentation are Propionibacterium shermanii or Pseudomonas denitrificans, which can synthesize Vitamin B12 under controlled bioreactor conditions. This method ensures a consistent 99% purity required for pharmaceutical and supplement-grade materials.

Manufacturing Process

The production of Vitamin B12 Cyanocobalamin 99% Powder USP involves several precise steps:

1. Fermentation

Selected bacterial strains are cultured in large bioreactors. Nutrients, temperature, and pH are strictly monitored for optimal vitamin production.

2. Extraction & Isolation

After fermentation, the broth is centrifuged and filtered to isolate Vitamin B12. Impurities are removed using activated carbon and ion exchange resins.

3. Conversion to Cyanocobalamin

The vitamin B12 is converted into its stable cyanocobalamin form by adding cyanide ions under controlled conditions.

4. Crystallization & Drying

The cyanocobalamin is crystallized, washed, and dried into a fine, reddish powder.

5. Quality Control

Each batch is tested according to USP standards for purity (≥99%), microbial content, heavy metals, and residual solvents.

How to Uses of Cyanocobalamin Powder?

Vitamin B12 Cyanocobalamin 99% USP Powder is widely used in:

1. Dietary supplements: Capsules, tablets, powders, effervescent tablets

2. Fortified foods and beverages: Cereals, energy drinks, meal replacements

3. Pharmaceutical formulations: B12 injection solutions or chewable tablets

4. Animal feed additives: For livestock, poultry, and pet nutrition

5. Cosmetic formulations: For skin-brightening and anti-fatigue serums

Customer Solution Case from Maxmedchem

1. Dietary Supplement Brand in the Australia

A leading Australia nutraceutical company

Need: A stable, high-purity form of Vitamin B12 for a new line of energy-boosting supplements targeted at busy professionals.

Solution: Maxmedchem Supplied with Cyanocobalamin 99% powder in 500kg drums, meeting strict USP standards. The powder was integrated into multivitamin gummies and capsules, offering 1000 mcg per serving.

Outcome: The product line launched with strong customer reviews citing increased energy and mental clarity. Repeat wholesale orders tripled within 6 months.

2. Energy Drink Manufacturer

Spain-based beverage startup

Need: A water-soluble, highly stable form of Vitamin B12 to add to energy drinks for fitness enthusiasts.

Solution: Customized spray-dried Cyanocobalamin 99% powder with improved solubility and flavor masking.

Outcome: The energy drink line achieved regulatory approval and entered 100+ health stores nationwide.

Vitamin B12 Cyanocobalamin 99% Powder is a cornerstone ingredient in modern health products. Whether you’re formulating dietary supplements or fortifying functional foods, sourcing high-purity Cyanocobalamin from a verified wholesale supplier in the USA ensures quality, compliance, and customer satisfaction. As B2B demand grows, securing dependable supply chains and bulk pricing will drive long-term success.

Contact Us for Wholesale Orders

Interested in premium Bulk Vitamin B12 Cyanocobalamin 99% Powder for your business? Contact us sales team today to discuss bulk pricing, MOQ, Price and customized Packaging options. We look forward to serving you.

*Tip: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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