Benzydamine Hydrochloride is an indazole non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-edema properties. Unlike other NSAIDs, benzydamine hydrochloride does not inhibit cyclooxygenases (COX) but stabilizes membranes, resulting in local anesthesia; inhibits the production of pro-inflammatory cytokines; inhibits the generation of reactive oxygen species by neutrophils; inhibits leukocyte aggregation and adhesion; and exhibits antimicrobial properties. (Source: NCI Thesaurus (NCIt)
Product Name: | Benzydamine hydrochloride |
Synonyms: | LABOTEST-BB LT00771795;BENZYDAMINE HCL;BENZYDAMINE HYDROCHLORIDE;1-BENZYL-3-[3-(DIMETHYLAMINO)-PROPOXY]-1H-INDAZOLE HYDROCHLORIDE;epirotin;imotryl;indolin;n,n-dimethyl-3-((1-(phenylmethyl)-1h-indazol-3-yl)oxy)-1-propanaminhydro |
CAS: | 132-69-4 |
MF: | C19H23N3O.ClH |
MW: | 345.87 |
EINECS: | 205-076-0 |
Product Categories: | ROBINUL;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate |
Mol File: | 132-69-4.mol |
Melting point | 147-153°C |
storage temp. | 2-8°C |
form | neat |
Water Solubility | Soluble in water, ethanol, chloroform, n-butanol or DMSO /n |
Merck | 14,1122 |
InChIKey | HNNIWKQLJSNAEQ-UHFFFAOYSA-N |
CAS DataBase Reference | 132-69-4(CAS DataBase Reference) |
In practice it is usually used as monohydrochloride salt.
The major side effects of benzydamine hydrochloride are oral numbness (reported prevalence: 10 percent), and oral burning/stinging (reported prevalence: 8 percent). Oral discomfort appears to be more of a problem in patients with extensive ulceration/infammation. The oral discomfort can sometimes be improved by diluting the benzydamine hydrochloride with an equal volume of water.It is thought that benzydamine hydrochloride does not precipitate peptic ulceration.
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Benzydamine Hydrochloride is an indazole non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-edema properties. Unlike other NSAIDs, benzydamine hydrochloride does not inhibit cyclooxygenases (COX) but stabilizes membranes, resulting in local anesthesia; inhibits the production of pro-inflammatory cytokines; inhibits the generation of reactive oxygen species by neutrophils; inhibits leukocyte aggregation and adhesion; and exhibits antimicrobial properties. (Source: NCI Thesaurus (NCIt)
Product Name: | Benzydamine hydrochloride |
Synonyms: | LABOTEST-BB LT00771795;BENZYDAMINE HCL;BENZYDAMINE HYDROCHLORIDE;1-BENZYL-3-[3-(DIMETHYLAMINO)-PROPOXY]-1H-INDAZOLE HYDROCHLORIDE;epirotin;imotryl;indolin;n,n-dimethyl-3-((1-(phenylmethyl)-1h-indazol-3-yl)oxy)-1-propanaminhydro |
CAS: | 132-69-4 |
MF: | C19H23N3O.ClH |
MW: | 345.87 |
EINECS: | 205-076-0 |
Product Categories: | ROBINUL;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate |
Mol File: | 132-69-4.mol |
Melting point | 147-153°C |
storage temp. | 2-8°C |
form | neat |
Water Solubility | Soluble in water, ethanol, chloroform, n-butanol or DMSO /n |
Merck | 14,1122 |
InChIKey | HNNIWKQLJSNAEQ-UHFFFAOYSA-N |
CAS DataBase Reference | 132-69-4(CAS DataBase Reference) |
In practice it is usually used as monohydrochloride salt.
The major side effects of benzydamine hydrochloride are oral numbness (reported prevalence: 10 percent), and oral burning/stinging (reported prevalence: 8 percent). Oral discomfort appears to be more of a problem in patients with extensive ulceration/infammation. The oral discomfort can sometimes be improved by diluting the benzydamine hydrochloride with an equal volume of water.It is thought that benzydamine hydrochloride does not precipitate peptic ulceration.
Email us at: info@maxmedchem.com
