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LAPPACONITINE HYDROBROMIDE (97792-45-5) C32H45BrN2O8

  • Chemical Name: LAPPACONITINE HYDROBROMIDE
  • CAS No.: 97792-45-5
  • MF: C32H45BrN2O8
  • MW: 665.61
  • Specification: USP|EP|BP
  • Purity:97%+or as customer requested
  • Categories: Pyridines;Inhibitors;Miscellaneous Natural Products
  • Test method: HPLC
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LAPPACONITINE HYDROBROMIDE Introduction 


Lappaconitine hydrobromide, a diterpene alkaloid, is a drug for the treatment of cardiac arrhythmias. IC50 value: Target: A natural product for anti-cardiac arrhythmias In vitro: Lappaconitine hydrobromide was found to exert an inhibitory effect on inward tetrodotoxin-sensitive sodium currents without changing their voltage dependence [1]. In vivo: The effect of Lappaconitine hydrobromide on aconitine--induced arrhythmias is due to modulation of genes encoding Na(+)-, K(+)-, Ca(2+)-channels, conducting ionic currents (I(Na), I(to), I(Ks), I(K1), I(CaT)), which are involved in the formation of different phases of the action potential [2]. Lappaconitine hydrobromide was found to be beneficial both in ventricular and supraventricular premature beats. Oral allapinine usually showed its effect 40-60 minutes following its administration, its maximum action being 4-5 hours later, its duration was some 8 hours. The optimal dose of the drug amounted to 75 mg/day [3].

Allapinine Basic Information 


Product Name: LAPPACONITINE HYDROBROMIDE
Synonyms: Lappaconitine Hydrobromide And Glucose Injection;Lappaconitine Hydrobromide 97792-45-5;Lappaconitine Hydrobromide, CP;LAPPACONITINE HBR;LAPPACONITINE HYDROBROMIDE;ALLAPININE;ALLAPININE HYDROBROMIDE;(1-alpha,14-alpha,16-beta)-monohydrobromide
CAS: 97792-45-5
MF: C32H45BrN2O8
MW: 665.61
Product Categories: Pyridines; Inhibitors; Miscellaneous Natural Products
Mol File: 97792-45-5.mol

Allapinin Chemical Structure

LAPPACONITINE HYDROBROMIDE            

Lappaconitine Hydrobromide Chemical Properties


Melting point  223-226 ºC
storage temp.  2-8°C

LAPPACONITINE HYDROBROMIDE Storage


Powder -20°C 3 years

4°C 2 years
In solvent -80°C 6 months

-20°C 1 month


MSDS: MSDS available

COA: COA can be available if you send us inquiry.

Email us at: info@maxmedchem.com for more details.

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