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Brexpiprazole(913611-97-9)C25H27N3O2S

  • Chemical Name:Brexpiprazole
  • CAS No.:913611-97-9
  • MF:C25H27N3O2S
  • MW:433.57
  • Purity:≥99% or according to customer requested
  • Product Categories: API;Intermediates & Fine Chemicals;Pharmaceuticals; Inhibitors
  • Test method: HPLC
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What is Brexpiprazole?

Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors. Brexpiprazole is approved for the treatment of schizophrenia, and as an adjunctive treatment for major depressive disorder (MDD). Although it failed Phase II clinical trials for ADHD, it has been designed to provide improved efficacy and tolerability (e.g., less akathisia, restlessness and/or insomnia) over established adjunctive treatments for major depressive disorder (MDD). (Source: DrugBank)

Basic information     
Product Name: Brexpiprazole
Synonyms: Brexpiprazole INN; Brexpiprazole JAN; Brexpiprazole USAN
CAS: 913611-97-9
MF: C25H27N3O2S
MW: 433.57
EINECS: 811-628-7
Product Categories: API; Intermediates & Fine Chemicals; Pharmaceuticals; Inhibitors
Chemical Structure

Brexpiprazole            

Chemical Properties
           
Boiling point  675.2±55.0 °C(Predicted)
density  1.245±0.06 g/cm3(Predicted)
pka 11.22±0.70(Predicted)
Brexpiprazole Uses And Synthesis

Brexpiprazole is an atypical antipsychotic used in the treatment of schizophrenia and major depressive disorders. Brexpiprazole has been associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of clinically apparent acute liver injury.


Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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