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Cefaclor Monohydrate (70356-03-5) C15H16ClN3O5S

  • Chemical Name: Cefaclor monohydrate
  • CAS No.: 70356-03-5
  • MF: C15H16ClN3O5S
  • MW:385.82
  • Specification: USP|EP|BP
  • Purity:90%-99% or As customer requested
  • Appearance:White to Orange to Green powder to crystal
  • Chemical Properties:White Crystalline Solid
  • Solubility:Slightly soluble in water, practically insoluble in methanol and in methylene chloride.
  • Test method: HPLC

Cefaclor Monohydrate Introduction   

Cefaclor is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. (Source: NCI Thesaurus (NCIt))

Ceclor Basic information        
Product Name: Cefaclor monohydrate
Synonyms: (7R)-3-Chloro-7-[[(R)-aminophenylacetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt;Muco-panoral; (6R,7R)-7-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3-chloro-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; (6R,7R)-7-[[(2R)-2-azanyl-2-phenyl-ethanoyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; Cefaclor (400 mg); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-aMino-2-phenylacetyl]aMino]-3-chloro-8-oxo-, hydrate (1:1),(6R,7R)-; CEFACLOR HYDRATE
CAS: 70356-03-5
MF: C15H16ClN3O5S
MW: 385.82
EINECS: 641-991-5
Product Categories: Heterocycles; Intermediates & Fine Chemicals; Chiral Reagents; Pharmaceuticals; Sulfur & Selenium Compounds
Mol File: 70356-03-5.mol

Distaclor Chemical Structure

Cefaclor monohydrate           

Alfatil Chemical Properties           
Melting point  >180°C (dec.)
storage temp.  -20?C Freezer
solubility  Slightly soluble in water, practically insoluble in methanol and in methylene chloride.
form  neat
CAS DataBase Reference 70356-03-5(CAS DataBase Reference)

Cefaclor Monohydrate Usage And Synthesis

Chemical Properties Crystalline Solid
Uses Antibacterial; Bacterial transpeptidase inhibitor
Second-generation cephalosporin antibiotic. Antibacterial
Contact allergens Cefaclor is a semisynthetic cephalosporin antibiotic, related to cefalexin, and a frequent inducer of serum sickness-like reactions.

MSDS: MSDS available

COA: COA can be available if you send us inquiry.

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