Cefaclor Monohydrate is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor Monohydrate binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes.
PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of Cefaclor Monohydrate interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Ceclor Basic information
| Product Name: | Cefaclor monohydrate |
| Synonyms: | (7R)-3-Chloro-7-[[(R)-aminophenylacetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt;Muco-panoral; (6R,7R)-7-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3-chloro-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; (6R,7R)-7-[[(2R)-2-azanyl-2-phenyl-ethanoyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; Cefaclor (400 mg); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-aMino-2-phenylacetyl]aMino]-3-chloro-8-oxo-, hydrate (1:1),(6R,7R)-; CEFACLOR HYDRATE |
| CAS: | 70356-03-5 |
| MF: | C15H16ClN3O5S |
| MW: | 385.82 |
| EINECS: | 641-991-5 |
| Product Categories: | Heterocycles; Intermediates & Fine Chemicals; Chiral Reagents; Pharmaceuticals; Sulfur & Selenium Compounds |
| Mol File: | 70356-03-5.mol |
| Melting point | >180°C (dec.) |
| storage temp. | -20?C Freezer |
| solubility | Slightly soluble in water, practically insoluble in methanol and in methylene chloride. |
| form | neat |
| CAS DataBase Reference | 70356-03-5(CAS DataBase Reference) |
| Chemical Properties | Crystalline Solid |
| Uses | Antibacterial; Bacterial transpeptidase inhibitor |
| Second-generation cephalosporin antibiotic. Antibacterial | |
| Contact allergens | Cefaclor is a semisynthetic cephalosporin antibiotic, related to cefalexin, and a frequent inducer of serum sickness-like reactions. |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
Cefaclor Monohydrate is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor Monohydrate binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes.
PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of Cefaclor Monohydrate interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Ceclor Basic information
| Product Name: | Cefaclor monohydrate |
| Synonyms: | (7R)-3-Chloro-7-[[(R)-aminophenylacetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt;Muco-panoral; (6R,7R)-7-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3-chloro-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; (6R,7R)-7-[[(2R)-2-azanyl-2-phenyl-ethanoyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; Cefaclor (400 mg); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-aMino-2-phenylacetyl]aMino]-3-chloro-8-oxo-, hydrate (1:1),(6R,7R)-; CEFACLOR HYDRATE |
| CAS: | 70356-03-5 |
| MF: | C15H16ClN3O5S |
| MW: | 385.82 |
| EINECS: | 641-991-5 |
| Product Categories: | Heterocycles; Intermediates & Fine Chemicals; Chiral Reagents; Pharmaceuticals; Sulfur & Selenium Compounds |
| Mol File: | 70356-03-5.mol |
| Melting point | >180°C (dec.) |
| storage temp. | -20?C Freezer |
| solubility | Slightly soluble in water, practically insoluble in methanol and in methylene chloride. |
| form | neat |
| CAS DataBase Reference | 70356-03-5(CAS DataBase Reference) |
| Chemical Properties | Crystalline Solid |
| Uses | Antibacterial; Bacterial transpeptidase inhibitor |
| Second-generation cephalosporin antibiotic. Antibacterial | |
| Contact allergens | Cefaclor is a semisynthetic cephalosporin antibiotic, related to cefalexin, and a frequent inducer of serum sickness-like reactions. |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
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