Clindamycin Hydrochloride

Description

Clindamycin Hydrochloride is the hydrochloride salt form of clindamycin, a semi-synthetic, chlorinated broad spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin hydrochloride is used as a solid in capsules.

Clindamycin hydrochloride Basic information

Product Name:	Clindamycin hydrochloride
Synonyms:	Clindaymcin Hydrochloride BP98,USP25,EP97;L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride;CLINDAMYCINHYDROCHLORIDE,CRYSTAL;CLINDAMYCINHYDROCHLORIDE,USP;Clindamycin hydrochloride, Antibiotic for Culture Media Use Only;CLINDAMYCIN HC;Lujiemycin;monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio
CAS:	21462-39-5
MF:	C18H34Cl2N2O5S
MW:	461.44
EINECS:	244-398-6
Product Categories:	Antimicrobial; API; Antibiotic Explorer; Peptide Synthesis/Antibiotics; CLINSOL; antibiotic; Carbohydrates & Derivatives; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals;

Clindamycin hcl Chemical Structure

Clindamycin hydrochloride

Cleocin hydrochloride Chemical Properties

Melting point	141°C
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL, clear, colorless
form	neat
BRN	4070786
InChIKey	AUODDLQVRAJAJM-XJQDNNTCSA-N
CAS DataBase Reference	21462-39-5(CAS DataBase Reference)

Cleocin hydrochloride Usage And Synthesis

Chemical Properties	White Solid
Uses	antibacterial, inhibits protein synthesis
	Clindamycin hydrochloride is a salt of clindamycin, a semi-synthetic lincosamide. The hydrochloride salt forms at the basic N-ethylproline moiety and is the preferred pharmaceutical formulation. Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin hydrochloride acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin hydrochloride has been extensively studied with over 8,000 literature citations.
	Labelled Clindamycin. Semi-synthetic antibiotic prepared from Lincomycin;Labeled Clindamycin, intended for use as an internal standard for the quantification of Clindamycin by GC- or LC-mass spectrometry.
Therapeutic Function	Antibacterial

Cleocin hydrochloride Other Information

Clindamycin is recommended for the treatment of a widevariety of upper respiratory, skin, and tissue infections causedby susceptible bacteria. Its activity against streptococci,staphylococci, and pneumococci is indisputably high, and it isone of the most potent agents available against somenon–spore-forming anaerobic bacteria, the Bacteroides spp.in particular.

MSDS: MSDS available.

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