Does Hydrolyzed Centella Asiatica Extract in Powder Type Safe

Yes, Hydrolyzed Centella Asiatica Extract in powder form is generally considered safe for topical use in cosmetic formulations, as long as it is sourced from reputable suppliers and used in appropriate concentrations. The extract is derived from the Centella Asiatica plant, which has a long history of use in traditional medicine for its skin-healing, anti-inflammatory, and anti-aging properties.

However, as with any cosmetic ingredient, there are important factors to consider to ensure safety during formulation, application, and use.

What is Hydrolyzed Centella Asiatica Extract？

Centella Asiatica, also known as Gotu Kola, is a medicinal herb traditionally used in Asian medicine for its skin-healing and rejuvenating properties. The plant is rich in bioactive compounds, including triterpenoids, saponins, flavonoids, and phenolic acids. The key active compounds:

• Madecassoside: Known for its strong anti-inflammatory and antioxidant properties. It helps reduce redness, calm irritation, and speed up the healing process.
• Asiaticoside: Known for its skin-healing and regenerative properties, it stimulates the production of collagen and elastin.
• Asiatic Acid: Offers anti-aging benefits by promoting collagen synthesis, improving skin elasticity, and fighting oxidative stress.
• Madecassic Acid: A potent compound known for its ability to regenerate skin cells and repair damaged skin tissue.

How is the Solubility of Hydrolyzed Centella Asiatica Extract？

Cosmetic raw material suppliers Hydrolyzation is the process of breaking down complex molecules (like proteins or large saponins) into smaller, more soluble peptides or compounds through the addition of water or enzymes. In the case of Hydrolyzed Centella Asiatica Extract, this process involves breaking down the Centella Asiatica extract to produce a more bioavailable version of its active compounds.

1. Water Solubility

Hydrolyzed Centella Asiatica Extract is highly water-soluble because the hydrolysis process breaks down the larger compounds into smaller, water-soluble peptides, saponins, and other bioactive molecules. This increased solubility in water allows the extract to be easily incorporated into water-based formulations such as:

• Toners
• Serums
• Essences
• Hydrating gels
• Sheet masks

Water solubility ensures that the active compounds (such as Madecassoside, Asiaticoside, Asiatic Acid) can be delivered effectively to the skin. When dissolved in water, these bioactive compounds can penetrate the skin barrier more easily and provide their soothing, healing, and hydrating effects.

Solubility in Water-Based Formulations:

• Hydrolyzed Centella Asiatica Extract typically dissolves easily in room temperature or slightly warm water (around 20-30°C).
• The concentration of the extract in a water-based formulation typically ranges from 0.5% to 5% depending on the intended purpose (e.g., calming, hydrating, anti-aging effects).

2. Solubility in Other Solvents (e.g., Alcohol, Glycerin)

Although water is the primary solvent, Hydrolyzed Centella Asiatica Extract can also exhibit some degree of solubility in alcohol-based or glycerin-based solutions, though its solubility in alcohol is typically lower than in water. It may dissolve in low concentrations of ethanol or glycerin, which are commonly used as solvents in cosmetic formulations. However, the water phase is usually the dominant phase in most skincare products.

• Ethanol (Alcohol): While ethanol (typically in concentrations of 10%-40%) can dissolve some active ingredients from Centella, its solubility is generally less compared to water. However, it can still be used as a solvent in alcohol-based toners or serums.
• Glycerin or Propylene Glycol: These solvents, which are commonly used for their humectant properties, can dissolve some of the bioactive compounds from the extract. However, they are typically used alongside water to help with formulation stability.

3. Solubility in Oil-Based Formulations

Hydrolyzed Centella Asiatica Extract is not readily soluble in oil (lipophilic) or non-polar solvents because its bioactive compounds are hydrophilic (water-loving). Therefore, it does not dissolve well in oil-based formulations like oil serums, balms, or creams that lack a significant water phase.

However, when emulsified with an emulsifier (to form an oil-water mixture), the extract can be included in oil-in-water emulsions, where the water phase will solvate the hydrolyzed Centella extract.

4. Considerations for Formulation

When formulating with Hydrolyzed Centella Asiatica Extract, it’s important to keep in mind the following solubility factors:

• Use in Water-Based Products:
  Hydrolyzed Centella Asiatica Extract is best used in water-based formulations (e.g., serums, toners, mists, or masks) where its solubility is optimal. In these formulations, it will dissolve easily and deliver its active ingredients effectively to the skin.
• Emulsification in Creams or Lotions:
  In creams, lotions, or emulsified formulations, Hydrolyzed Centella can be incorporated into the water phase of the formulation. These emulsions (which combine water and oil) allow the water-soluble extract to remain stable and effective.
• Avoid High Heat:
  When adding Hydrolyzed Centella Asiatica Extract to formulations, avoid high temperatures, as extreme heat can potentially degrade the active compounds and affect solubility. It is best to add it during the cool-down phase of formulation, especially in products like creams and lotions.

Benefits of Hydrolyzed Centella Asiatica Extract in Powder Type

Hydrolyzed Centella Asiatica Extract is a refined, water-soluble form of the Centella Asiatica plant that is broken down into smaller, more absorbable molecules through hydrolysis. This makes the extract more effective in skincare products, offering benefits such as:

• Soothing and anti-inflammatory effects
• Skin regeneration and wound healing
• Anti-aging and collagen-boosting properties
• Moisture retention and hydration

Uses of Hydrolyzed Centella Asiatica Extract

Hydrolyzed Centella Asiatica Powder is a versatile ingredient that can be used in a wide range of skincare formulations, including:

• Face Serums and Creams
  Adding Hydrolyzed Centella to serums or creams helps to calm inflammation, improve hydration, and promote skin regeneration.
• Sheet Masks
  It can be incorporated into hydrating and soothing sheet masks, providing an intensive calming treatment for irritated skin.
• Spot Treatments
  For acne-prone skin or individuals with scars, it can be applied directly to blemishes to reduce redness, promote healing, and prevent scarring.
• Hydrating Toners or Essences
  It works well in toners or essences to provide deep hydration, balance skin pH, and enhance the penetration of other active ingredients.
• Cleansers & Face Washes
  Centella Extract in powder form can also be included in cleansers to soothe and hydrate while gently cleansing the skin.

Skin Types Suitable for Hydrolyzed Centella Asiatica Extract

• Sensitive Skin
  Centella’s calming and healing properties make it ideal for sensitive skin types that are prone to irritation, redness, or reaction to environmental stressors.
• Acne-Prone Skin
  The anti-inflammatory and wound-healing qualities make it a go-to ingredient for acne-prone skin, reducing inflammation and accelerating healing of post-acne scars.
• Aging or Mature Skin
  Centella’s ability to promote collagen synthesis and reduce fine lines and wrinkles makes it an excellent anti-aging ingredient.
• Dry and Dehydrated Skin
  The extract’s moisturizing and barrier-repairing abilities make it beneficial for dry or dehydrated skin, helping to lock in moisture and prevent trans-epidermal water loss.
• Combination Skin
  Its gentle, balancing effects help regulate moisture levels without overloading the skin, making it suitable for combination skin.

Formulation for Hydrolyzed Centella Asiatica Extract in Powder Type

When formulating with Hydrolyzed Centella Asiatica Powder, here are some general guidelines to ensure the best results:

• Recommended Dosage
  Typically, Hydrolyzed Centella is used at a concentration of 0.5% to 5% in skincare formulations. For optimal effectiveness, start with a lower concentration and gradually increase as needed, depending on the desired effect.
• Solubilization
  To incorporate the powdered form into a formulation, dissolve it in water-based formulations or incorporate it into emulsions. Ensure proper solubilization to avoid clumping and enhance product performance.
• pH Range
  Centella Asiatica extract works best in a slightly acidic to neutral pH range (approximately 4.5 to 6.5), which aligns with the skin’s natural pH.
• Formulation Compatibility
  Hydrolyzed Centella is generally compatible with other active ingredients like peptides, ceramides, hyaluronic acid, and niacinamide. However, avoid pairing it with extremely acidic ingredients (such as strong AHAs or BHAs) in the same formulation to preserve its efficacy.

1. Safety Considerations

Hydrolyzed Centella Asiatica Extract is considered safe for topical use in cosmetic formulations, but as with any active ingredient, it’s important to conduct patch testing before use, especially for individuals with highly sensitive skin. Here are a few safety tips:

• Patch Test
  Always perform a patch test on a small area of skin before incorporating new products containing Centella to ensure no adverse reactions occur.
• Sensitivity
  If you have a known allergy or sensitivity to plants in the Apiaceae family (e.g., parsley, carrots), it’s advisable to consult a dermatologist before using Centella-based products.
• Concentration
  Avoid using excessively high concentrations (above the recommended 5%) as it could lead to skin irritation or sensitivity, especially for sensitive skin types.

2. Dosage Guidelines for Use

For cosmetic formulations, the typical recommended usage is as follows:

• Creams, Serums, Lotions
  0.5% to 3% concentration is effective for calming and repair.
• Sheet Masks or Toners
  1% to 5% concentration for more intense hydrating and soothing effects.
• Targeted Treatments (e.g., Acne or Scar Care)
  1% to 2% concentration, applied directly to affected areas or incorporated into spot treatments.

International Regulations and Compliance

Hydrolyzed Centella Asiatica Extract is generally recognized as safe (GRAS) in most regions and is approved for use in cosmetics in various countries. However, it is important to comply with the specific regulations of the region in which you are selling the products. Some general regulatory considerations include:

• EU (European Union)
  Centella Asiatica is listed as a safe cosmetic ingredient and is widely used in EU formulations. Ensure all claims are substantiated and comply with the Cosmetic Regulation (EC) No 1223/2009.
• US (United States)
  The FDA considers Centella Asiatica as safe for use in cosmetics, provided that it meets the guidelines set forth in the Federal Food, Drug, and Cosmetic Act.
• Asia-Pacific (APAC)
  Centella is commonly used in skincare products throughout countries like South Korea, Japan, and China. Ensure compliance with local cosmetic regulations, which may vary by region.
• Other Markets
  For markets like Canada or Australia, Hydrolyzed Centella Asiatica Extract is recognized as a safe ingredient. However, always verify local regulatory requirements before launching products.

How does Maxmedchem Factory Manufacture Hydrolyzed Centella Asiatica Extract?

1. Filtration and Purification

Maxmedchem Factory Hydrolyzed Centella Asiatica Extract After hydrolysis, the extract will contain a range of broken-down compounds, including both the desired bioactive ingredients and potentially some impurities. To purify the extract:

• Filtration
  The extract is filtered to remove any residual plant fibers, undissolved particles, and any large molecular debris that was not broken down during hydrolysis.
• Concentration
  The extract is then concentrated to ensure a potent final product. This may be done using vacuum evaporation, where water or solvent is evaporated under low pressure to prevent heat damage, resulting in a more concentrated extract.
• Drying
  If you are producing Hydrolyzed Centella Asiatica Extract in Powder Form, the extract is then dried. This can be done using spray-drying (where the concentrated extract is sprayed into a hot chamber, turning it into a fine powder) or freeze-drying (where the extract is frozen and then subjected to a vacuum to remove moisture). Freeze-drying helps to preserve more of the plant’s active ingredients.

2. Quality Control and Testing

Once Maxmedchem Manufacturer have the final extract in powder form, it’s essential to conduct rigorous quality control testing to ensure that the extract is safe, effective, and consistent. Key tests include:

• Purity and Composition
  High-performance liquid chromatography (HPLC) can be used to identify and quantify the active compounds (such as Madecassoside, Asiaticoside, etc.) in the hydrolyzed extract.
• Microbial Testing
  To ensure that the final product is free from harmful bacteria or mold, it should undergo microbial testing.
• Heavy Metals and Pesticides
  Testing for the presence of heavy metals (e.g., lead, arsenic) and pesticide residues is critical for safety, especially when the product is going to be sold in regulated markets.
• pH and Stability Testing
  You should test the pH of the extract to ensure it falls within a suitable range (typically between 4.5-6.5 for skincare use). Stability tests should also be conducted to confirm the extract remains effective over time under different storage conditions.

Packaging and Storage

After passing quality control, the final Hydrolyzed Centella Asiatica Extract in Powder Form is carefully packaged in moisture-proof, airtight containers to preserve its potency. It should be stored in a cool, dry place to prevent degradation and maintain its efficacy. If you need wholesale cosmetic ingredients and COA support, Please Contact us!