How much do you know about creatine monohydrate?

**How much do you know about creatine monohydrate?**

Creatine monohydrate (CrM) is one of the healthiest supplements research has shown, with approximately 70% of studies showing that creatine monohydrate is an important fortifier (enhancing performance) in a variety of sports. But most people simplify its effect to “creatine makes you stronger” and “you just leave water in your body”.

While this is part of the supplement’s function, it does underestimate the nitrogenous compound, as its operation is more complex than simple cell swelling.

What is creatine?

Creatine is a nitrogenous compound stored in the muscles of mammals and fish, 95% of which is stored in skeletal muscle (making animal meat an excellent dietary source). In the human body, 60% is phosphocreatine (PCr) and 40% is creatine.

For maximal or extreme exercise <30s, the body activates the anaerobic energy system. This includes ATP stored in the body (the body’s source of energy), the ATP-PCr system and the anaerobic sugar breakdown system.

Training at this exercise intensity does not provide enough time to generate energy (ATP) through the more sustainable aerobic (with oxygen) pathway. Therefore, an immediate source of energy is needed at this time. This is when creatine comes into play. Phosphocreatine (PCr) is responsible for the resynthesis of ATP (adenosine triphosphate) from ADP (adenosine diphosphate), providing a rapid source of energy. When the phosphate “breaks down” from ATP, the bonds of ADP are broken, leaving ADP behind and releasing energy. Creatine kinase can facilitate the reaction between ADP and phosphate to resynthesize (regenerate) ATP. Stored ATP and PCr are at their maximum in 5-8 seconds, 88-100% depleted, 30-60 seconds to recover 50%, and about 5 minutes for full recovery.

If our bodies can produce creatine, why we need to supplement it?

By supplementing Creatine monohydrate, we can increase the body’s creatine storage from 125mmol.kg to 160mmol.kg, increase the maximum energy produced and maintained by the body, prolong the training time to failure and increase the number of repetitions, and the rate of physical recovery, That is, how long the body can regenerate energy.

The benefits of Creatine monohydrate supplementation

1. By depleting our own higher levels of creatine, we are able to induce faster PCr resynthesis in the body, resulting in longer bodily recovery and improvement in an anaerobic system.

2. During anaerobic exercise (resistance training), the body accumulates metabolites (such as lactate and H+ ions). The accumulation of H+ ions inhibits energy production and reduces athletic peak performance.

3. It can remove H+ ions generated during PCr resynthesis. Athletes looking for endurance are well worth considering!

Experiments have demonstrated that Creatine monohydrate helps maintain lean body mass (LBM) and increases the cross-sectional diameter of muscle fibers, especially type II fibers.

Type II fibers are strongly associated with heavy lifting and explosive lifting. Increasing the type II fibers in the body makes the muscle tissue larger and more visible.

Muscle hypertrophy (growth) requires the branched-chain amino acid (BCAA) leucine, without which anabolism (building muscle) cannot take place, so leucine is known as the “anabolic trigger”.

The literature shows that Creatine monohydrate can reduce leucine oxidation and breakdown, increasing its availability and muscle retention (or potential growth) – definitely an added bonus for muscle. Creatine monohydrate has been shown to correlate with increased expression (activity) of the anabolic hormone insulin-like growth factor-1 (IGF-1), which further aids muscle maintenance.

What motivates it to retain nutrients?

This brings us to the controversial “moisture retention”. The “swelling” of cells ingested by creatine is due to the influx of water. However, it’s not just water that flows into the cells. The increase in cellular permeability caused by Creatine monohydrate releases important nutrients such as leucine as the water flows. The influx of water into cells is also associated with hydration, which can prolong exercise time and improve exercise performance.

Maxmedchem has been working at the production of Creatine monohydrate for over ten years and most of the Creatine monohydrate powder are used for dietary supplement development.

And we also have warehouses in US, free samples could be offered if you have any demand on our products.