Natamycin could be used at both food and pharma fields

Natamycin could be used at food production?

Natamycin is a natural, safe and efficient biological fungal inhibitor. It is widely used in the preservation of cheese, meat products, beverages and other foods. It can effectively kill and inhibit the growth of mold, yeast and other fungi in food, and can inhibit the production of mycotoxins, and can effectively reduce the cost of food production and prolong the shelf life of food.

Natamycin – nearly white or cream yellow crystalline powder. It is an odorless, tasteless, low-dose and high-safety food preservative. Natamycin is a white to milky white odorless and tasteless crystalline powder obtained by controlled fermentation of Streptomyces nata, usually in the form of an enol structure. Its mechanism of action is to combine with fungal ergosterol and other sterol groups to inhibit ergosterol biosynthesis, thereby distorting the cell membrane, eventually leading to leakage and cell death. The surface treatment of dough with natamycin in bakery products can obviously prolong the shelf life.

Natamycin benefits

Natamycin relies on its lactone ring structure to interact with sterol compounds on the fungal cell membrane to form antibiotic-sterol compounds, thereby destroying the structure of the fungal cytoplasmic membrane. The hydrophilic part (polyol part) of macrolide forms water pores on the membrane, which damages the permeability of the cell membrane, which in turn causes the exudation of amino acids, electrolytes and other substances in the bacteria, and the bacteria die. When there are sterol compounds on the cell membrane of some microorganisms, natamycin has no effect on it, so natamycin only inhibits fungi and does not have antibacterial activity against bacteria and viruses.

Natamycin common uses at pharma field

Natamycin is used to treat fungal infections, including Candida, Aspergillus, Fusarium, etc., and is also used in eye drops or oral medicines, where natamycin is less absorbed by the body. When taken orally, there is little absorption from the gastrointestinal tract, making it unsuitable as a drug for systemic infections. Natamycin is also used in eye drops, and its 5% natamycin content is indicated for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by microorganisms, including Fusarium solani keratitis.

We have Natamycin powder stock available in US warehouses and competitive price could be offered.

Contact us for free samples at: info@maxmedchem.com