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Hydrocortisone
- Chemical Name: Hydrocortisone
- CAS No.:50-23-7
- MF: C21H30O5
- MW:362.47
- Purity:≥99% or according to customer requested
- Color: White powder
- Product Categories: Intermediates& Fine Chemicals; Inhibitors; Pharmaceuticals; API
- Test method: HPLC
Description
What is Hydrocortisone?
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses.
Basic information
| Product Name: | Hydrocortisone |
| Synonyms: | Cortisol; Hydrasson; Hydrocortisyl; |
| CAS: | 50-23-7 |
| MF: | C21H30O5 |
| MW: | 362.47 |
| EINECS: | 200-020-1 |
| Product Categories: | Pharmaceutical intermediates; Intermediates& Fine Chemicals; Inhibitors; Pharmaceuticals; API |
Chemical Structure
Chemical Properties
| Melting point | 211-214 °C(lit.) |
| alpha | 166 º (c=1, C2H5OH 25 ºC) |
| Boiling point | 414.06°C (rough estimate) |
| density | 1.0812 (rough estimate) |
| refractive index | 1.6120 (estimate) |
| Fp | 220°C |
| storage temp. | -20°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| color | White |
| Water Solubility | 319.7mg/L(25 ºC) |
| Decomposition | 220 ºC |
| Merck | 14,4787 |
| BRN | 1354819 |
| Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
Hydrocortisone Uses And Synthesis
| Chemical Properties | crystalline white powder |
| Uses | Principle glucocorticoid hormone produced by adrenal cortex. An anti-inflammatory hormone. |
| glucocorticoid, antiinflammatory | |
| Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. |
Technical Support & Resources
Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
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