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Hygromycin B (31282-04-9) C20H37N3O13

  • Chemical Name: Hygromycin B
  • CAS No.:31282-04-9
  • MF:C20H37N3O13
  • MW: 527.52
  • Specification: USP|EP|BP
  • Purity:98%,99% or As customer requested
  • Color:faintly brown to brown
  • Solubility:Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.
  • Product Categories:antibiotic;Inhibitors
  • Test method: HPLC
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Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. (Source: DrugBank)

Also, Hygromycin B is a trisaccharide aminoglycoside with a terminal cyclitol produced by Streptomyces hygroscopicus, reported by researchers at Eli Lily in the early 1950s. Hygromycin B belongs to the destomycin family of aminoglycosides which contain a unique cyclic structure linking the terminal saccharide. Hygromycin B exhibits broad spectrum antibiotic and anthelmintic activity, and is used as a feed additive for swine and poultry.

Hygromycin B Basic information  
Product Name: Hygromycin B
Synonyms: antihelmycin; hydromycinb; hygromix2.4; hygromix-8; hygrovetine; Hygromycin Solution; Hygromix; 
CAS: 31282-04-9
MF: C20H37N3O13
MW: 527.52
EINECS: 250-545-5
Product Categories: antibiotic; Inhibitors

Hygromycin B Chemical Structure

Hygromycin B            

Hygromycin antibiotic Chemical Properties    
Melting point  160-180°C
alpha  D20 +20.2° (c = 1 in water)
Boiling point  608.13°C (rough estimate)
density  1.4252 (rough estimate)
refractive index  1.6300 (estimate)
storage temp.  2-8°C
solubility  H2O: 50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 30 days.
pka 7.1, 8.8(at 25℃)
form  powder
color  faintly brown to brown
PH pH (25g/l, 25℃ ) : 9.5~12.5
Water Solubility  Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.
Merck  14,4852
BRN  6755837

Hygromycin antibiotic Usage And Synthesis


Chemical Properties White to off-white lyophilized powder
Uses

antibacterial, anthelmintic; LD50 ip (rat) 63mg/Kg
Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome
MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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