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L Serine Bulk Powder
- Chemical Name: L-Serine
- CAS No.:56-45-1
- MF:C3H7NO3
- MW:105.09
- Purity:98% or according to customer requirements
- Color:White
- Product Categories: Amino Acids;alpha-Amino Acids;Biochemistry;Nutritional Supplements;L-Amino Acids;Food & Feed ADDITIVES;
- Test method: HPLC
Description
What is L Serine Bulk Powder?
L serine bulk powder has also been used to treat psychosis, Alzheimer’s disease, schizophrenia, epilepsy, and other neurological conditions.
In addition, the safety of L-serine is generally supported by animal dosing and human clinical trials examining its therapeutic effects. The focus on l serine powder bulk‘s therapeutic potential as a general treatment for numerous CNS diseases and injuries is what makes this review so significant. It is possible to use l-serine powder bulk as an effective neuroprotective agent in clinical settings due to its wide range of functions.
Basic information
Chemical Structure
Chemical Properties
| Melting point | 222 °C (dec.) (lit.) |
| alpha | 15.2 º (c=10, 2N HCl) |
| Boiling point | 197.09°C (rough estimate) |
| density | 1.6 |
| refractive index | 1.4368 (estimate) |
| Fp | 150°C |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| pka | 2.19(at 25℃) |
| color | White |
| PH | 5-6 (100g/l, H2O, 20℃) |
| optical activity | [α]20/D +13.5±0.5°, c = 5% in 5 M HCl |
| Water Solubility | 250 g/L (20 ºC) |
| λmax | λ: 260 nm Amax: 0.05 λ: 280 nm Amax: 0.05 |
| Sublimation | 150 ºC |
| Merck | 14,8460 |
| BRN | 1721404 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | MTCFGRXMJLQNBG-REOHCLBHSA-N |
L Serine Bulk Powder Usage And Synthesis
1) Amyotrophic Lateral Sclerosis (ALS)
The use of l serine bulk powder as a treatment for ALS has only recently been investigated. The breakdown of nerve cells is the root cause of ALS, which ultimately results in fatal muscle weakness.
L-serine supplementation for six months slowed the disease’s progression in 20 ALS patients [17].
L-serine inhibited the activity of defective amino acids that contribute to the development of ALS in test tubes [18, 19].
There is not enough evidence to draw solid conclusions; More research is required.
2) Ongoing Exhaustion Condition
Ongoing exhaustion condition (CFS) causes side effects like outrageous sluggishness, agony, and distress. These symptoms may be correlated with low serine levels in the blood, according to preliminary research [20].
After 15 weeks of treatment, l serine bulk powder supplementation significantly reduced physical symptoms in 28 patients with chronic fatigue syndrome [21].
3) Signs and symptoms of HSAN1
HSAN1 is a brain disease that makes the legs and feet feel nothing.
L-serine supplementation for ten weeks slowed the progression of HSAN1 in 14 patients. Additionally, it enhanced leg sensation [22].
4) Improvement in Sleep
The quality of your sleep may be improved by taking a small amount of L-serine before bed.
Consuming L-serine for four nights improved sleep quality and ability to fall asleep in 53 participants who struggled to sleep [23].
5) Seizures
L serine powder bulk is being studied as a complementary treatment option as a possible link to seizures [24].
Low levels of L-serine are found in some epileptic patients. Two patients experienced reductions in seizures, involuntary movements, muscle spasms, and uncontrolled muscle stiffness after receiving L-serine treatment for a week [25].
L-serine, on the other hand, may not be completely effective in some diseases that cause seizures, like 3-phosphoglycerate dehydrogenase deficiency [26].
L-serine’s efficacy and safety in treating various kinds of seizures ought to be the subject of well-designed trials.
There is no clinical evidence to support the use of L-serine for any of the conditions listed in this section in animal and cellular research (lack of evidence). The following is an outline of the current creature and cell-based examinations. They should serve as a guide for future research efforts, but they should not be interpreted as promoting any health benefits.
6) Alzheimer’s Disease
L-serine powder bulk reduced the formation of Alzheimer’s disease-associated proteins (neurofibrillary tangles) in the brain. L-serine exposure can reduce these tangles, according to cell studies [27, 19].
Four months of daily L-serine intake significantly reduced the number of Alzheimer’s disease-associated proteins in monkeys with neurofibrillary tangles [28].
D-serine may also assist in the diagnosis of Alzheimer’s disease. Some Alzheimer’s patients have low levels of D-serine [29].
However, D-serine levels in Alzheimer’s patients’ and unaffected brains were found to be identical in other studies [30].
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