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Oxolinic Acid

  • Chemical Name:Oxolinic acid
  • CAS No.:14698-29-4
  • MF: C13H11NO5
  • MW:261.23
  • Specification: USP|EP|BP
  • Purity:98%,99% or As customer requested
  • Color: White
  • Solubility:Soluble in 0.5N NaOH with warming
  • Product Categories: Intermediates & Fine Chemicals;veterinary medicine,APIs,pharmaceutical raw material;Pharmaceuticals;
  • Test method: HPLC


Oxolinic acid is a quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. 

A synthetic antibiotic, Oxolinic acid is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. It has a role as an antiinfective agent, an antibacterial drug, an enzyme inhibitor, an antimicrobial agent and an antifungal agent. 

Oxolinic acid is a quinolinemonocarboxylic acid, an organic heterotricyclic compound, an aromatic carboxylic acid, an oxacycle and a quinolone antibiotic. It is a conjugate acid of an oxolinate. 

Oxolinic acid Basic information  

Product Name: Oxolinic acid
Synonyms: OXOLINIC ACID; 5,8-DIHYDRO-5-ETHYL-8-OXO-1,3-DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLIC ACID;5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid;5-ETHYL-8-OXO-5,8-DIHYDRO-[1,3]DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLIC ACID
CAS: 14698-29-4
MF: C13H11NO5
MW: 261.23
EINECS: 238-750-8
Product Categories: APIs;Heterocyclic Compounds; Heterocycles;Intermediates & Fine Chemicals; pharmaceutical raw material; Pharmaceuticals

Oxolinic acid Chemical Structure

Oxolinic acid            

Prodoxal API Chemical Properties     

Melting point  314-316°C (dec.)
Boiling point  473℃
density  1.3038 (rough estimate)
refractive index  1.5500 (estimate)
Fp  >110°(230°F)
storage temp.  2-8°C
solubility  Soluble in 0.5N NaOH with warming
form  Crystalline Powder
pka 5.94±0.20(Predicted)
color  White
Water Solubility  3.214mg/L(temperature not stated)
Sensitive  Light Sensitive
Merck  13,7014
BRN  620635
Stability: Stable. Combustible.

Prodoxal API Usage And Synthesis

Chemical Properties Crystalline Solid

Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia
Quinolone antibacterial.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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