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Oxytetracycline Hydrochloride (2058-46-0) C22H25ClN2O9

  • Chemical Name: Oxytetracycline hydrochloride
  • CAS No.: 2058-46-0
  • MF: C22H25ClN2O9
  • MW: 496.89
  • Specification: USP|EP|BP
  • Purity: 98%,99% or As customer requested
  • Color: yellow
  • Water Solubility:>100 g/L
  • Product Categories:  Pharmaceutical intermediate;Amines; Intermediates & Fine Chemicals; Pharmaceuticals; 
  • Test method: HPLC

Oxytetracycline Hydrochloride is the hydrochloride salt form of oxytetracycline, a tetracycline derivative produced by Streptomyces rimosus exhibiting antimicrobial activity. Oxytetracycline hydrochloride interferes with binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing peptide elongation and inhibiting protein synthesis. It is often used to treat skin conditions. (Source: NCI Thesaurus (NCIt))

Oxytetracycline hydrochloride Basic information   
Product Name: Oxytetracycline hydrochloride
Synonyms: hydrocyclin; liquamycin injectable; mepatar; 5-hydroxytetracycline hydrochloride; GEOMYCIN; AQUACYCLINE
CAS: 2058-46-0
MF: C22H25ClN2O9
MW: 496.89
EINECS: 218-161-2
Product Categories: Pharmaceutical intermediate;Amines; Intermediates & Fine Chemicals; Pharmaceuticals; 

Oxytetracycline hydrochloride Chemical Structure

Oxytetracycline hydrochloride           

Oxytetracycline hcl Chemical Properties  
Melting point  180°C
alpha  -188~-200°(D/20℃)(c=1,0.1mol/l HCl) (calculated on the dried basis)
storage temp.  0-6°C
solubility  Freely soluble in water, sparingly soluble in ethanol (96 per cent). Solutions in water become turbid on standing, owing to the precipitation of oxytetracycline.
form  crystalline
color  yellow
PH 2.0~3.0 (10g/l, 25℃)
Water Solubility  >100 g/L
λmax 360nm(H2O)(lit.)
Sensitive  Light Sensitive
Merck  14,6976
BRN  3853107
Oxytetracycline hcl Usage And Synthesis  
Chemical Properties Yellow Crystalline Solid
Uses Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
Uses Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial
Therapeutic Function Antibiotic
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