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Oxytetracycline Hydrochloride
- Chemical Name: Oxytetracycline hydrochloride
- CAS No.: 2058-46-0
- MF: C22H25ClN2O9
- MW: 496.89
- Specification: USP|EP|BP
- Purity: 98%,99% or As customer requested
- Color: yellow
- Water Solubility：>100 g/L
- Product Categories: Pharmaceutical intermediate;Amines; Intermediates & Fine Chemicals; Pharmaceuticals;
- Test method: HPLC
Description
Oxytetracycline hydrochloride is effective against Actinomyces, Rickettsia, Mycoplasma and Chlamydia and is therefore recommended for the treatment of Mortellaro, Moraxella bovis conjunctivitis in calves, atrophic Rhinitis and MMA syndrome in pigs, Pasteurella multocida and Mycoplasma infections in poultry. The antibiotic effect is bacteriostatic.
Oxytetracycline hydrochloride Basic information
| Product Name: | Oxytetracycline hydrochloride |
| Synonyms: | hydrocyclin; liquamycin injectable; mepatar; 5-hydroxytetracycline hydrochloride; GEOMYCIN; AQUACYCLINE |
| CAS: | 2058-46-0 |
| MF: | C22H25ClN2O9 |
| MW: | 496.89 |
| EINECS: | 218-161-2 |
| Product Categories: | Pharmaceutical intermediate;Amines; Intermediates & Fine Chemicals; Pharmaceuticals; |
Oxytetracycline hydrochloride Chemical Structure
Oxytetracycline hcl Chemical Properties
| Melting point | 180°C |
| alpha | -188～-200°(D/20℃)(c=1,0.1mol/l HCl) (calculated on the dried basis) |
| storage temp. | 0-6°C |
| solubility | Freely soluble in water, sparingly soluble in ethanol (96 per cent). Solutions in water become turbid on standing, owing to the precipitation of oxytetracycline. |
| form | crystalline |
| color | yellow |
| PH | 2.0～3.0 (10g/l, 25℃) |
| Water Solubility | >100 g/L |
| λmax | 360nm(H2O)(lit.) |
| Sensitive | Light Sensitive |
| Merck | 14,6976 |
| BRN | 3853107 |
Oxytetracycline hcl Usage And Synthesis
| Chemical Properties | Yellow Crystalline Solid |
| Uses | Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. |
| Uses | Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial |
| Therapeutic Function | Antibiotic |
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