Cloxacillin Sodium is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
Cloxacillin Sodium binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.
| Product Name: | Sodium cloxacillin monohydrate |
| Synonyms: | bactopen; cloxacillin sodium monohydrate; CLOXACILLIN SODIUM SALT MONOHYDRATE;CLOXACILLIN SODIUM SALT HYDRATE;CLOXACILLIN SODIUM SALT N-HYDRATE;CLOXACILLIN SODIUM SALT HYDRATE VETRANAL;CLOXACILLIN SODIUM EPC |
| CAS: | 7081-44-9 |
| MF: | C19H19ClN3NaO6S |
| MW: | 475.88 |
| EINECS: | 629-588-2 |
| Product Categories: | Pharmaceutical raw chemicals; API; antibiotic; Biochemistry |
| Melting point | 170℃ |
| Boiling point | 689℃ |
| Fp | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | solid |
| Water Solubility | Soluble in water |
| Merck | 13,2444 |
| BRN | 5403885 |
| Chemical Properties | White or almost white, hygroscopic, crystalline powder. |
| Uses | Penicillin antibacterial. |
| Clinical Use | The chlorine atom ortho to the position of attachment of thephenyl ring to the isoxazole ring enhances the activity ofcloxacillin sodium, [3-(o-chlorophenyl)-5-methyl-4-isoxazolyl]penicillin sodium monohydrate (Tegopen), over that ofoxacillin, not by increasing its intrinsic antibacterial activitybut by enhancing its oral absorption, leading to higher plasmalevels. In almost all other respects, it resembles oxacillin. |
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
Cloxacillin Sodium is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
Cloxacillin Sodium binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.
| Product Name: | Sodium cloxacillin monohydrate |
| Synonyms: | bactopen; cloxacillin sodium monohydrate; CLOXACILLIN SODIUM SALT MONOHYDRATE;CLOXACILLIN SODIUM SALT HYDRATE;CLOXACILLIN SODIUM SALT N-HYDRATE;CLOXACILLIN SODIUM SALT HYDRATE VETRANAL;CLOXACILLIN SODIUM EPC |
| CAS: | 7081-44-9 |
| MF: | C19H19ClN3NaO6S |
| MW: | 475.88 |
| EINECS: | 629-588-2 |
| Product Categories: | Pharmaceutical raw chemicals; API; antibiotic; Biochemistry |
| Melting point | 170℃ |
| Boiling point | 689℃ |
| Fp | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | solid |
| Water Solubility | Soluble in water |
| Merck | 13,2444 |
| BRN | 5403885 |
| Chemical Properties | White or almost white, hygroscopic, crystalline powder. |
| Uses | Penicillin antibacterial. |
| Clinical Use | The chlorine atom ortho to the position of attachment of thephenyl ring to the isoxazole ring enhances the activity ofcloxacillin sodium, [3-(o-chlorophenyl)-5-methyl-4-isoxazolyl]penicillin sodium monohydrate (Tegopen), over that ofoxacillin, not by increasing its intrinsic antibacterial activitybut by enhancing its oral absorption, leading to higher plasmalevels. In almost all other respects, it resembles oxacillin. |
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
