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- Chemical Name: TAUROURSODEOXYCHOLIC ACID
- CAS No.:14605-22-2
- MF:C26H45NO6S
- MW:499.7
- Purity:>98% or As customer requested
- Color:Silver
- Product Categories: Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Herb extract
- Test method: HPLC
Description
What is Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is the more hydrophilic form of ursodeoxycholic acid, which is the more abundant naturally produced bile acid in humans. Tauroursodeoxycholic acid, on the other hand, is produced abundantly in bears and has been used for centuries as a natural remedy in some Asian countries.
It is approved in Italy and Turkey for the treatment of cholesterol gallstones and is an investigational drug in China, Unites States, and Italy. Tauroursodeoxycholic acid is being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis. The only completed clinical trial thus far is a phase III clinical trial comparing tauroursodeoxycholic acid and ursofalk in PBC adult patients, but as of June 2013 no results of this trial have been published.(Source: DrugBank)
Basic information
| Product Name: | TAUROURSODEOXYCHOLIC ACID |
| Synonyms: | Tauroursodeoxycholate; Taurursodiol; Taurolite; |
| CAS: | 14605-22-2 |
| MF: | C26H45NO6S |
| MW: | 499.7 |
| EINECS: | 1308068-626-2 |
| Product Categories: | Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Herb extract |
Chemical Structure
Chemical Properties
| Melting point | 173-175°C |
| density | 1.216±0.06 g/cm3(Predicted) |
| refractive index | 46 ° (C=1, EtOH) |
| storage temp. | +15C to +30C |
| pka | 1.42±0.50(Predicted) |
| InChIKey | BHTRKEVKTKCXOH-LBSADWJPSA-N |
Usage And Synthesis
| Chemical Properties | Off-White Solid |
| Uses | Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways |
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Technical Support & Resources
Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
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