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  • CAS No.:14605-22-2
  • MF:C26H45NO6S
  • MW:499.7
  • Purity:>98% or As customer requested
  • Color:Silver
  • Product Categories: Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Herb extract
  • Test method: HPLC

What is Tauroursodeoxycholic acid?

Tauroursodeoxycholic acid is the more hydrophilic form of ursodeoxycholic acid, which is the more abundant naturally produced bile acid in humans. Tauroursodeoxycholic acid, on the other hand, is produced abundantly in bears and has been used for centuries as a natural remedy in some Asian countries. 

It is approved in Italy and Turkey for the treatment of cholesterol gallstones and is an investigational drug in China, Unites States, and Italy. Tauroursodeoxycholic acid is being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis. The only completed clinical trial thus far is a phase III clinical trial comparing tauroursodeoxycholic acid and ursofalk in PBC adult patients, but as of June 2013 no results of this trial have been published.(Source: DrugBank)

Basic information   
Synonyms: Tauroursodeoxycholate; Taurursodiol; Taurolite; 
CAS: 14605-22-2
MF: C26H45NO6S
MW: 499.7
EINECS: 1308068-626-2
Product Categories: Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Herb extract
Chemical Structure


Chemical Properties  
Melting point  173-175°C
density  1.216±0.06 g/cm3(Predicted)
refractive index  46 ° (C=1, EtOH)
storage temp.  +15C to +30C
pka 1.42±0.50(Predicted)
Usage And Synthesis
Chemical Properties Off-White Solid
Uses Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways

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Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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