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Product Name:Pharmaceuticals Grade 2-(AMINOMETHYL)PHENOL
CAS No.: 354563-89-6
Specification: USP|EP|BP
Purity:99% or as customer requested
Product Categories: Intermediates & Fine Chemicals;PHARMACEUTICALS;
Test method: HPLC


What is 2-(aminomethyl)phenol?

2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study in Older Adults).

2 AMINOMETHYL PHENOL Basic information     

Synonyms: BUTTPARK 18�9-57; RARECHEM AL BW 0003; 1-[alpha-(4,6-Dimethoxypyrimidin-2-yl)benzyl]piperazine 95+%;Pyrimidine, 4,6-dimethoxy-2-(phenyl-1-piperazinylmethyl)-; 2-(AMINOMETHYL)PHENOL USP/EP/BP
CAS: 354563-89-6
MF: C17H22N4O2
MW: 314.38
EINECS: 814-044-0
Product Categories: Pharmaceuticals, Fine chemicals..etc
Mol File: 354563-89-6.mol

2 Hydroxybenzylamine Chemical Structure


Salicylamine Chemical Properties


Melting point 127-131 °C
Boiling point 463.8±45.0 °C(Predicted)
density 1.163±0.06 g/cm3(Predicted)
pka 8.88±0.10(Predicted)
CAS DataBase Reference 354563-89-6(CAS DataBase Reference)

2 AMINOMETHYL PHENOL Certificate of Analysis


Item Standard Test Results
Identification A.H-NMR:Comply with the structure Complies
B.LC-MS:Comply with the structure Complies
C.The IR spectrum of sample should be identical with that of reference standard. Complies
D.HPLC-ESI-MSThe retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. Complies
Crystallinity meets the requirements. Complies
Loss on drying ≤2.0% 0.19%
Heavy metals ≤10 ppm <10ppm
Water ≤1.0% 0.1%
Sulphated ash ≤0.5% determined on 1.0 g. 0.009%
Residue on ignition ≤0.1% 0.03%
Related Substances Unspecified impurities: for each impurity ≤0.10% <0.10%
Total Impurity ≤0.5% 0.18%
Purity ≥99.0% 99.7%
Assay 99.0%~101.0% (anhydrous substance). 99.8%


Microbiological Analysis

Total plate count ≤1000cfu/g Complies
Yeast & Moulds ≤100cfu/g Complies
E. Coli.  Absent Negative
Salmonella  Absent Negative
S.aureus  Absent Negative
Storage Preserve in well-closed,light-resistant and airtight containers. Complies


Application areas:

1. Medicinal chemistry: As an intermediate in drug synthesis, it participates in the preparation of biologically active compounds.
2. Dye synthesis: used as raw material for dye synthesis, giving dyes color and special properties.
3. Organic synthesis: In the process of organic synthesis, it serves as a key intermediate and catalyst to promote the construction of complex molecules.

Stability and storage:

2-(AMINOMETHYL)PHENOL shows good stability when stored in a dry and cool environment. Avoid direct sunlight and high temperature environments, and ensure good sealing to extend the shelf life of the product.

Safety Precautions:

Please follow laboratory safety procedures when using this product. Avoid direct contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

Packaging specifications:

2-(AMINOMETHYL)PHENOL provides packaging of different specifications to meet the different needs of customers. Common packaging includes bottles, barrels, etc. For detailed information, please refer to the product specification sheet.


2-(AMINOMETHYL)PHENOL, as a multifunctional organic synthetic compound, has broad application prospects. High purity, good solubility and stability make it an indispensable material in many fields. We are committed to providing high-quality products and excellent services to meet the various needs of our customers. Please feel free to contact us with any further questions or customization needs.

MSDS: MSDS available

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