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Acetylsalicylic Acid

Product Name: Acetylsalicylic acid
CAS No.: 50-78-2

MF: C9H8O4
MW: 180.16
Purity: 98% Min or as Requested.
HS Code: 29182210
Test Method: HPLC
Chemical Property: White crystalline, with melting point 138~140 ℃, insoluble in water, soluble in alcohol, ether, etc.


What is Acetylsalicylic Acid

Acetylsalicylic acid, also known as aspirin, is an analgesic-antipyretic medicine made by salicylic acid interacting with acetic anhydride. It is a white crystalline powder, odorless, stable in dry air. It will be slowly hydrolyzed to be salicylic acid and acetic acid in moist air, and aqueous solution has acidic reaction. Slightly soluble in water, soluble in ethanol, ethyl ether, chloroform, sodium hydroxide solution and sodium carbonate solution. Pure acetylsalicylic acid has antipyretic analgesic, anti-inflammatory and anti-rheumatism effect, that’s why it is often used for fever, headache, muscle pain, neuralgia, rheumatic fever, acute rheumatic arthritis, gout, etc.; also it has antiplatelet aggregation effect, and can be used for prevention of arterial thrombosis, atherosclerosis, transient cerebral ischemia and myocardial infarction; in addition, acetylsalicylic acid also can be used in the treatment of biliary tract roundworm disease and athlete’s foot.



Product Name: Acetylsalicylic acid
Synonyms: O-ACETYLSALICYLIC ACID;O-ACETOXYBENZOIC ACID;2-Acetoxybenzoesre,Aspirin;2-Acetoxybenzoic acid~Aspirin;aspirin usp;o-Acetylsalicylic acid 2-Acetoxybenzoic acid;ASPIRIN (AECTAMINOPHIN);ACETYLSALICYLIC ACID BP2000
CAS: 50-78-2
MF: C9H8O4
MW: 180.16
EINECS: 200-064-1
Product Categories: Pharmaceutical; Aromatics Compounds; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals; Isotope; Lipid signaling; Anti-Allergic Agents, Antibiotic; LOPROX
Mol File: 50-78-2.mol


Acetylsalicylic acid            

Aspirin Usp Chemical Properties


Melting point  134-136 °C (lit.)
Boiling point  272.96°C (rough estimate)
density  1.35
refractive index  1.4500 (estimate)
Fp  250 °C
storage temp.  Store at RT.
solubility  H2O: 10 mg/mL at 37 °C
form  crystalline
color  white
pka 3.5(at 25℃)
Water Solubility  3.3 g/L (20 ºC)
Merck  14,851
BRN  779271
Stability: Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
CAS DataBase Reference 50-78-2(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 2-(acetyloxy)-(50-78-2)
EPA Substance Registry System Aspirin (50-78-2)

What’s the uses of Acetylsalicylic acid


1. Treats skin conditions. Used as far back as the fifth century B.C. by Hippocrates to ease aches and pains, salicylic acid, a derivative of pure acetylsalicylic acid (aspirin), is a powder extracted from the bark of a willow tree. It “helps remove excess oil and exfoliate dead cells on the skin’s surface,” says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City, adding that it’s “extremely useful in treating acne.”

2. Gets rid of dandruff. Because of its moisturizing qualities, the same salicylic acid contained in face washes is also an ingredient in many dandruff shampoos. “Applying acetylsalicylic acid mixed with shampoo to your scalp may help reduce scalp inflammation that causes dandruff and help exfoliate flakes on the skin,” says Zeichner.

3. Soothes stings and bites. Zeichner says aspirin, with its anti-inflammatory properties, may help reduce the redness, swelling, and pain from bug bites. Make an aspirin paste similar to the one used for problem skin or just dampen an uncoated aspirin and apply it to the affected area for a few minutes.

4. Removes stains. The salicylic acid in pure acetylsalicylic acid helps to neutralize stains by attacking the compounds found in sweat and breaking them down. Mix three crushed aspirins and half a cup of warm water in a bowl. Submerge the stained portion of the clothing into the bowl for a few hours. Afterwards, wash the shirt as usual. You can use any of the leftover mixture to remove nicotine or grass stains from hands by applying the solution and letting it sit for 15 minutes before washing hands thoroughly.

5. Makes your garden grow. Acetylsalicylic Acid works just as well outside as it does on your skin by activating the plants’ natural defenses and preventing the formation of fungus. It also increases growth rate.

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