Ampicillin Sodium

Description

Ampicillin Sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. Ampicillin sodium inhibits bacterial cell wall synthesis by binding to penicillin binding proteins, thereby inhibiting peptidoglycan synthesis, a critical component of the bacterial cell wall.

Ampicillin sodium Basic information

Product Name:	Ampicillin sodium
Synonyms:	D-6-(-Amino-phenylacetamido)penicillanicacidsodiumsalt;Domicillin;omnipen-n;pena/n;penbritin-s;penialmen;polycillin-n;principen/n
CAS:	69-52-3
MF:	C16H18N3NaO4S
MW:	371.39
EINECS:	200-708-1
Product Categories:	Antibiotic Explorer; veterinary medicine,soluble powder; Pharma; API; OMNIPEN; antibiotic; semisynthetic broad-spectrum penicillin; Pharmaceutical raw chemicals; Inhibitors
Mol File:	69-52-3.mol

Sodium ampicillin Chemical Structure

Ampicillin sodium

Ampicillin sodium salt Chemical Properties

Melting point	215 °C (dec.)(lit.)
alpha	+246～+272°
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL, clear, very faintly yellow
form	powder
color	white with slight yellow cast
PH	pH(100g/l, 25℃):8.0～10.0
Water Solubility	Freely soluble in water. Sparingly soluble in acetone
BRN	4119211
CAS DataBase Reference	69-52-3(CAS DataBase Reference)

Ampicillin sodium salt Usage And Synthesis

Chemical Properties	White or almost white powder or crystal. Soluble in water, slightly soluble in ethanol, insoluble in ether. Hygroscopic, when it is set at room temperature in an aqueous solution ,it gradually turns yellow,produces turbidity, decreases potency. Odorless, slightly bitter taste.
Uses	A semi-synthetic broad-spectrum penicillin,it is mainly used for treatment of penicillin-sensitive gram-positive bacteria, Escherichia coli, Proteus, Salmonella, Shigella and other.
production method	It is derived from the ampicillin salifying : Ampicillin is suspended in water, adjust to pH 9 with sodium hydroxide solution, dissolve and filter . The filtrate is added active carbon, and is filtered and the filtrate is dried at a low temperature, to obtain the product.
Category	Toxic substances