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Cemandil Sodium Salt
- Chemical Name: Cemandil sodium salt
- CAS No.:42540-40-9
- MF: C19H17N6NaO6S2
- MW: 512.49
- Specification: USP|EP|BP
- Purity:>98% or As customer requested
- Chemical Properties: White Solid
- Solubility：Freely soluble in water. Sparingly soluble in methanol
- Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
- Test method: HPLC
Description
Cemandil Sodium Salt, also called as Cefamandole Nafate, is the sodium salt form of cefamandole formyl ester. Cemandil Sodium Salt is a pro-drug that is hydrolyzed by plasma esterases to produce cefamandole, a semi-synthetic beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. (Source: NCI Thesaurus (NCIt))
Basic information
| Product Name: | Cemandil sodium salt |
| Synonyms: | Cemandil sodium salt; CEFAMANDOLE NAFATE; Cefamandole Nafate (250 mg); Cefamandole Nafate (200 mg) |
| CAS: | 42540-40-9 |
| MF: | C19H17N6NaO6S2 |
| MW: | 512.49 |
| EINECS: | 255-877-4 |
| Product Categories: | Intermediates & Fine Chemicals; Pharmaceuticals |
Chemical Structure
Chemical Properties
| Melting point | 190-193°C |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Freely soluble in water, sparingly soluble in methanol. |
| pka | 2.6-3.0(at 25℃) |
| form | neat |
| Water Solubility | Freely soluble in water. Sparingly soluble in methanol |
Usage And Synthesis
Chemical Properties: White Solid
Uses: Cephalosporin antibacterial.
Therapeutic Function: Antibiotic
Technical Support & Resources
Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
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