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Sisomycin Sulfate
- Chemical Name:Sisomycin Sulfate
- CAS No.:53179-09-2
- MF: C19H39N5O11S
- MW: 545.61
- Specification: USP|EP|BP
- Purity: 98%,99% or As customer requested
- Appearance: white to off-white
- Solubility：H2O: soluble50mg/mL
- Product Categories: SISEPTIN;Aminoglycosides Antibiotics;Antibacterial;Antibiotics;
- Test method: HPLC
Description
Sisomycin Sulfate, also called as Sisomicin Sulfate, which is the sulfate salt form of sisomicin, a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is strucurally similar to gentamicin but has a unique unsaturated diamino sugar. Of the aminoglycoside antibiotics, sisomicin has the greatest activity against gram-positive bacteria. (Source: NCI Thesaurus (NCIt))
Sisomycin Sulfate Basic information
| Product Name: | Sisomycin Sulfate |
| Synonyms: | 6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-d-glycero-hex-4-enopyranosyl-(1-4)); extramycin; Sisomicin sulfate, 580 IU/mg; pathomycin; sisomin |
| CAS: | 53179-09-2 |
| MF: | C19H39N5O11S |
| MW: | 545.61 |
| EINECS: | 258-414-4 |
| Product Categories: | SISEPTIN; Aminoglycosides Antibiotics; Antibacterial; Antibiotics; |
| Mol File: | 53179-09-2.mol |
Pathomycin Chemical Structure
Extramycin Chemical Properties
| Melting point | 70-73C |
| Boiling point | 155℃ |
| Fp | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | powder |
| color | white to off-white |
| optical activity | [α]25/D 100 to 110° in water (Specific rotation (anhydrous), C=1) |
| Water Solubility | Soluble in water |
| Merck | 14,8550 |
Sisomycin Sulfate Usage And Synthesis
| Uses | antibacterial, binds to ribosomes |
| Therapeutic Function | Antibiotic |
| Clinical Use | Although Sisomycin Sulfate has been approved for human use in theUnited States, it has not been marketed in this country. Itsantibacterial potency and effectiveness against aminoglycoside-inactivating enzymes resemble those of gentamicin.Sisomicin also exhibits pharmacokinetics and pharmacologicalproperties similar to those of gentamicin. |
| Safety Profile | Poison by intravenous,intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition itemits very toxic fumes of SOx and NOx. |
Maxmedchem, a global supplier of Sisomycin Sulfate, 53179-09-2 offers for your requirements of RND / Development quantities or commercials, based on status of the product. We can also offer its intermediates with supportive technical package required for evaluation.
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
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