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Chlorogenic Acid Caffeine

Product name: Chlorogenic acid

CAS No.: 327-97-9
MF: C16H18O9
Solubility: Soluble in ethanol and acetone
Purity: 99%
Chemical Properties: white to slightly yellowish-beige powder
HS Code: 29182900
Test Method: HPLC
 

Description

What is Chlorogenic Acid Caffeine?

Chlorogenic acid caffeine (CA) is a phenolic compound broadly tracked down in products of the soil (apples, pears, carrots, tomatoes, and yams) and in espresso and tea.71 Recent proof exhibited the searching, cell reinforcement, and antiapoptotic action of wholesale chlorogenic acid.72 In a murine model of cisplatin (CP)- prompted AKI,72 the chlorogenic acid caffeine intraperitoneally infused 48 hours after the CP infusion recuperated renal capability and decreased renal histologic irregularities concerning cylindrical rot, cast collection, and rounded dilatation. 

The wholesale chlorogenic acid-actuated histology improvement resembled the decrease of renal oxidative pressure and aggravation, as shown by the diminished articulation of cyclooxygenase-2 (COX-2) and growth corruption factor-α (TNF-α). Also, chlorogenic acid caffeine displayed a restraining impact on apoptosis and autophagy, as recommended by the concealment of p53, caspase-3, cyclin D1, and microtubule-related protein 1 light chain 3 isoform B (LC3B) articulation.

Basic information of Chlorogenic acid

Product Name:

Chlorogenic acid

Synonyms:

(1R,3R,4S,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxy-cyclohexane-1-carboxylic acid;CHLOROGENID ACID;CHLOROGENIC ACID(AHP);3-CAFFEOLYQUINICACID;3-[[3-(3,4-dihydroxyphenyl)-1-oxy-2-propenyl]oxy]-1,4,5-trihydroxy-1,[1S-(1 a , 3 β , 4 a , 5 a )];Chlorogenic Acid Hydrate;Cyclohexanecarboxylic acid,3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)- 1,4,5-trihydroxy-,(1S-(1-alpha,3-beta,4-alpha,5-alpha));Heriguard

CAS:

327-97-9

MF:

C16H18O9

MW:

354.31

EINECS:

206-325-6

Product Categories:

natural product;Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Plant Oils, Toxins, Phenolic Acids & Derivatives;Natural Plant Extract;Plant extract;Plant extracts;Herb extract;standardized herbal extract;caffeic acid;Chlorogenic acid;The group of Chlorogenic acid

Mol File:

327-97-9.mol

Caffeoylquinic Acids Chemical Structure

Chlorogenic acid

Chlorogenic Acid Hydrate Chemical Properties

Melting point

210 °C (dec.) (lit.)

alpha

-36 º (c=1, H2O)

Boiling point

407.55°C (rough estimate)

density

1.3594 (rough estimate)

refractive index

-37 ° (C=1, H2O)

storage temp.

0-6°C

solubility

Soluble in ethanol and acetone.

pka

3.91±0.50(Predicted)

form

Powder, Crystals, Needles and/or Chunks

color

White to almost white

Water Solubility

SOLUBLE IN HOT WATER

Merck

14,2142

InChIKey

CWVRJTMFETXNAD-JUHZACGLSA-N

CAS DataBase Reference

327-97-9(CAS DataBase Reference)

EPA Substance Registry System

Chlorogenic acid (327-97-9)

Chlorogenic Acid Caffeine Benefits

1. Chlorogenic Acid Appears To Reduce Blood Pressure

There have been numerous studies investigating the link between chlorogenic acid caffeine and blood pressure;

A randomized, controlled trial demonstrated that 140 mg per day of wholesale chlorogenic acid could decrease blood pressure. In this study, all participants who took chlorogenic acid had “significantly reduced” blood pressure readings shortly after ingestion compared to placebo

2. Chlorogenic Acid May Improve Glucose Regulation

Clinical trials demonstrate that wholesale chlorogenic acid intake lowers fasting levels of glucose and insulin levels, as well as lowering the postprandial response.

3. May Protect Against Heart Disease and Atherosclerosis

Human studies show that chlorogenic acid can reduce some of the risk factors for cardiovascular disease. Animal studies go one step further, and they demonstrate that chlorogenic acid caffeine helps prevent atherosclerosis.

4. Chlorogenic Acid Improves Endothelial Function in Human Studies

Studies demonstrate that wholesale chlorogenic acid improves flow mediated dilation and endothelial function.

5. Anti-Inflammatory Activity

There are claims that chlorogenic acid caffeine displays anti-inflammatory and antioxidant properties.

           

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