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Colistin Sulfate (1264-72-8) C52H98N16O13

  • Chemical Name:Colistin sulfate
  • CAS No.:1264-72-8
  • MF: 2(C52H98N16O13).5(H2SO4)
  • MW:2801.27
  • Specification: USP|EP|BP
  • Purity: 98%,99% or As customer requested
  • Chemical Properties: White to off-white powder.
  • Solubility:Soluble in water
  • Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Veterinaries;antibiotic;APIs;Inhibitors
  • Test method: HPLC

Colistin is a cyclic polypeptide antibiotic of the polymyxin family. It targets the cell membrane of bacteria, which ultimately leads to an altered cell permeability and cell death. It primarily targets gram-negative bacteria. Colistin has been used to study mannose-resistant haemagglutination, antibiotic resistance, and nephrotoxicity.

Polymyxin antibiotic. Binds to lipids on the cell cytoplasmic membrane. Disrupts cell wall integrity. Effective against Gram-negative bacteria. 

Colistin sulfate Basic information 
Product Name: Colistin sulfate
Synonyms: belcomycin; Animal Feed Additives colistin sulfate Colistin Sulfate; Animal Feed Additives colistin sulfate CAS 1264-72-8 Colistin Sulfate; COLISTINE SULFATE; COLISTIN SULPHATE PURE GRADE; Colistin sulphate premix 10% 40%; Polymyxin E . sulfate
CAS: 1264-72-8
MF: 2(C52H98N16O13).5(H2SO4)
MW: 2801.27
EINECS: 215-034-3
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Active Pharmaceutical Ingredients; Veterinaries; SYNCURINE; antibiotic; API; Inhibitors

Colistin sulfate Chemical Structure

Colistin sulfate            

Colistin sulphate Chemical Properties   
Melting point  200-220°C
storage temp.  2-8°C
solubility  H2O: soluble50mg/mL
form  powder
PH 4.0~6.0(10g/l, 25℃)
Water Solubility  Soluble in water
Merck  14,2479
Colistin sulphate Usage And Synthesis    
Chemical Properties White or almost white, hygroscopic powder.

neuromuscular blocker
Clinical Use Colistimethate sodium
Infections due to Ps. aeruginosa and other Gram-negative rods resistant to less toxic agents
Cystic fibrosis (inhalation therapy for pseudomonas infection)
Polymyxin B and colistin sulfate
Component of preparations for local application
Superficial infections with Ps. aeruginosa and to prevent the colonization of burns
Selective decontamination of the gut and as a paste for control of upper respiratory tract colonization in patients on prolonged mechanical ventilation (in combination with other agents)
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