As businesses in the pharmaceutical, nutraceutical, and research sectors increasingly recognize bulk food grade TUDCA supplement (tauroursodeoxycholic acid) powder value for liver support and cytoprotection, sourcing from certified, high‑purity bulk powder suppliers becomes essential.
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What is The Source?
Tauroursodeoxycholic acid (TUDCA, CAS 14605‑22‑2) is a taurine‑conjugated form of ursodeoxycholic acid (UDCA), present only in trace levels in human bile but abundant in traditional bear bile extracts. Modern manufacturing derives TUDCA via microbial or chemical conjugation methods to achieve food‑grade purity. Reputable suppliers typically source TUDCA raw material through controlled industrial synthesis or microbial fermentation, ensuring a white crystalline powder of ≥ 98–99 % purity
What is TUDCA Made from?
TUDCA (Tauroursodeoxycholic acid) is a bile acid that the body naturally produces through a microbial process. The body forms it when the bile acid ursodeoxycholic acid (UDCA) conjugates with the amino acid taurine. While humans produce only small amounts, bear bile contains it in higher concentrations. Today, laboratories also synthesize TUDCA, often as a dietary supplement.
What Does TUDCA Do in the Body?
TUDCA is a bile acid — but what does that mean? Bile represents a complex fluid made of bile acids, phospholipids, cholesterol, water, electrolytes, and other organic molecules. Bile acids are the most functional component of bile. They help us digest and absorb the fat-soluble vitamins A, D, E and K, break down food and cholesterol, and destroy harmful pathogens that enter the digestive system on our food. Through these processes, bile and TUDCA help the body eliminate waste, excrete unnecessary cholesterol, and regulate your metabolism. In particular, bile acids convert and eliminate around 500 mg of cholesterol from the body every day.
Manufacturing Process of TUDCA (tauroursodeoxycholic acid)
1. Raw TUDCA substrate is produced from cholesterol derivatives through multi‑step enzymatic or chemical hydroxylation and side‑chain cleavage in controlled reactors, followed by microbial conversion by gut‑flora‑type strains to yield ursodeoxycholic acid (UDCA) .
2. The conjugation with taurine is then performed—chemically linking UDCA and taurine—to generate TUDCA.
3. Purification steps include crystallization, filtration, HPLC verification (≥98–99 % assay), moisture and heavy‑metal testing (<1 % drying loss, <10 ppm total heavy metals, microbial limit tests).
4. Final bulk powder is packaged (e.g. 1 kg foil pouches, 25 kg drums), with lead time often 3–7 working days and shelf life around 3 years when stored cool and dry.
Essence medchem Co., Ltd offers high‑purity (≥ 99%) food‑grade TUDCA powder in bulk sizes, packaged under certified quality systems (ISO, FDA, HACCP, Kosher, Halal). Its product is widely exported across Europe, North America, and Australia.
What We Offer to Distributors (EU & USA)
As a verified USA based manufacturer with decades of experience, the company welcomes OEM inquiries, sample orders (e.g. 10 g free sample), and U.S warehouse support. Contact us today to request a distributor starter pack or Best price tudca bulk powder.
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