Levocetirizine Dihydrochloride is the dihydrochloride salt form of the active levorotatory enantiomer of cetirizine, levocetirizine; a third generation, non-sedating, selective histamine H1 receptor antagonist, with antihistamine, anti-inflammatory and potential anti-angiogenic activities. Levocetirizine competes with endogenous histamine for binding at peripheral H1-receptor sites on the effector cell surface.
This prevents the negative symptoms associated with histamine release and an allergic reaction. In addition, as histamine plays an important role in angiogenesis during an allergic inflammatory reaction, blocking the action of histamine may modulate the expression of proangiogenic factors and thus may prevent angiogenesis. As a third-generation histamine H1 receptor antagonist, levocetirizine has fewer side effects than most second-generation antihistamines.
| Product Name: | Levocetirizine dihydrochloride |
| Synonyms: | LEVOCETIRIZINE 2HCL;LEVOCETIRIZINE DIHCL;LEVOCETIRIZINE DIHYDROCHLORIDE;LEVOCETIRIZINE HCL;LEVOCETRIZINE DIHYDROCHLORIDE;[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride;[2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-ACETIC ACID 2HCL;(R)-Cetirizine (hydrochloride) |
| CAS: | 130018-87-0 |
| MF: | C21H27Cl3N2O3 |
| MW: | 461.81 |
| EINECS: | 641-093-3 |
| Product Categories: | Antibiotics; Levocitirizine 2HCl; API's; Levocetirizine; Histamine receptor; API |
| Mol File: | 130018-87-0.mol |
| Melting point | 215-220°C |
| alpha | D25 -12.79° (c = 1 in water) |
| storage temp. | room temp |
| solubility | H2O: ≥23mg/mL |
| form | powder |
| Merck | 14,2022 |
| CAS DataBase Reference | 130018-87-0(CAS DataBase Reference) |
| Uses | Anti Histaminic |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
Levocetirizine Dihydrochloride is the dihydrochloride salt form of the active levorotatory enantiomer of cetirizine, levocetirizine; a third generation, non-sedating, selective histamine H1 receptor antagonist, with antihistamine, anti-inflammatory and potential anti-angiogenic activities. Levocetirizine competes with endogenous histamine for binding at peripheral H1-receptor sites on the effector cell surface.
This prevents the negative symptoms associated with histamine release and an allergic reaction. In addition, as histamine plays an important role in angiogenesis during an allergic inflammatory reaction, blocking the action of histamine may modulate the expression of proangiogenic factors and thus may prevent angiogenesis. As a third-generation histamine H1 receptor antagonist, levocetirizine has fewer side effects than most second-generation antihistamines.
| Product Name: | Levocetirizine dihydrochloride |
| Synonyms: | LEVOCETIRIZINE 2HCL;LEVOCETIRIZINE DIHCL;LEVOCETIRIZINE DIHYDROCHLORIDE;LEVOCETIRIZINE HCL;LEVOCETRIZINE DIHYDROCHLORIDE;[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride;[2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-ACETIC ACID 2HCL;(R)-Cetirizine (hydrochloride) |
| CAS: | 130018-87-0 |
| MF: | C21H27Cl3N2O3 |
| MW: | 461.81 |
| EINECS: | 641-093-3 |
| Product Categories: | Antibiotics; Levocitirizine 2HCl; API's; Levocetirizine; Histamine receptor; API |
| Mol File: | 130018-87-0.mol |
| Melting point | 215-220°C |
| alpha | D25 -12.79° (c = 1 in water) |
| storage temp. | room temp |
| solubility | H2O: ≥23mg/mL |
| form | powder |
| Merck | 14,2022 |
| CAS DataBase Reference | 130018-87-0(CAS DataBase Reference) |
| Uses | Anti Histaminic |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.
