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Azelastine Hydrochloride (79307-93-0) C22H25Cl2N3O

  • Chemical Name: Azelastine hydrochloride
  • CAS No.: 79307-93-0
  • MF:C22H25Cl2N3O
  • MW: 418.36
  • Specification: USP|EP|BP
  • Purity:98%+ or As customer requested
  • Color: White or almost white, crystalline powder.
  • Categories: Antihistaminic; Astelin; Intermediates & Fine Chemicals; Pharmaceuticals; Histamine receptor
  • Solubility:DMSO: >10mg/mL
  • Test method: HPLC
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Azelastine hydrochloride Description    


Azelastine Hydrochloride is the hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. (Source: NCI Thesaurus (NCIt))

Azelastine Hcl Basic information



Product Name: Azelastine hydrochloride
Synonyms: a5610;azeptin;e-0659;w-2979m;AZELASTINE HCL;AZELASTINE HYDROCHLORIDE;4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one hydrochloride;4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride
CAS: 79307-93-0
MF: C22H25Cl2N3O
MW: 418.36
EINECS: 620-469-0
Product Categories: Antihistaminic; Astelin; Intermediates & Fine Chemicals; Pharmaceuticals; Histamine receptor
Mol File: 79307-93-0.mol

           

Astelin Chemical Structure

Azelastine hydrochloride            

Allergodil Chemical Properties

           

Melting point  225--2290C
storage temp.  -20°C Freezer
solubility  DMSO: >10mg/mL
form  powder
color  white to off-white
Merck  14,906
Stability: Incompatible with strong oxidizing agents.
CAS DataBase Reference 79307-93-0(CAS DataBase Reference)

Azelastine Hydrochloride Usage And Synthesis


Description Azelastine hydrochloride is an orally effective antihistamine useful in the treatment of asthma and nasal allergy. It appears to inhibit release of histamine, in addition to antagonizing its action.
Chemical Properties White or almost white, crystalline powder.
Uses Orally active H1-hystamine receptor antagonist. Antihistaminic
Definition ChEBI: The hydrochloride salt of azelastine.

MSDS: MSDS available


COA: COA can be available if you send us inquiry.


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