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Azelastine Hydrochloride
- Chemical Name: Azelastine hydrochloride
- CAS No.: 79307-93-0
- MF:C22H25Cl2N3O
- MW: 418.36
- Specification: USP|EP|BP
- Purity:98%+ or As customer requested
- Color: White or almost white, crystalline powder.
- Categories: Antihistaminic; Astelin; Intermediates & Fine Chemicals; Pharmaceuticals; Histamine receptor
- Solubility:DMSO: >10mg/mL
- Test method: HPLC
Description
Azelastine hydrochloride Description
Azelastine Hydrochloride is the hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity.
Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. (Source: NCI Thesaurus (NCIt))
Azelastine Hcl Basic information
Product Name: | Azelastine hydrochloride |
Synonyms: | a5610;azeptin;e-0659;w-2979m;AZELASTINE HCL;AZELASTINE HYDROCHLORIDE;4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one hydrochloride;4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride |
CAS: | 79307-93-0 |
MF: | C22H25Cl2N3O |
MW: | 418.36 |
EINECS: | 620-469-0 |
Product Categories: | Antihistaminic; Astelin; Intermediates & Fine Chemicals; Pharmaceuticals; Histamine receptor |
Mol File: | 79307-93-0.mol |
Astelin Chemical Structure
Allergodil Chemical Properties
Melting point | 225–2290C |
storage temp. | -20°C Freezer |
solubility | DMSO: >10mg/mL |
form | powder |
color | white to off-white |
Merck | 14,906 |
Stability: | Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 79307-93-0(CAS DataBase Reference) |
Azelastine Hydrochloride Usage And Synthesis
Description | Azelastine hydrochloride is an orally effective antihistamine useful in the treatment of asthma and nasal allergy. It appears to inhibit release of histamine, in addition to antagonizing its action. |
Chemical Properties | White or almost white, crystalline powder. |
Uses | Orally active H1-hystamine receptor antagonist. Antihistaminic |
Definition | ChEBI: The hydrochloride salt of azelastine. |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
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